Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:Alexa Fluor 647 (MBS212060A647))
Mouse anti-Dog, Mink CD42a Monoclonal Antibody | anti-CD42a antibody
MOUSE ANTI HUMAN CD42a
Purified IgG - liquid
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/100
Preparation
Fusion Partners
Shelf Life: 18 months from date of despatch.
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:Alexa Fluor 647 (MBS212060A647))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:Alexa Fluor 647 (MBS212060A647))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:RPE (MBS213563))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:RPE (MBS213563))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:FITC (MBS210636))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:FITC (MBS210636))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:Biotin (MBS210316))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a:Biotin (MBS210316))
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a)
Testing Data
(Staining of human peripheral blood platelets with Mouse anti Human CD42a)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Uniprot Description
GPIX: The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS); also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q21.3
Cellular Component: integral to plasma membrane; plasma membrane
Biological Process: platelet activation; cell adhesion; blood coagulation; blood coagulation, intrinsic pathway
Disease: Bernard-soulier Syndrome
Research Articles on CD42a
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Product Notes
The CD42a gp9 (Catalog #AAA212060) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI HUMAN CD42a reacts with Dog, Mink and may cross-react with other species as described in the data sheet. AAA Biotech's CD42a can be used in a range of immunoassay formats including, but not limited to, Flow cytometry (FC/FACS), Immunoprecipitation (IP). Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/100. Researchers should empirically determine the suitability of the CD42a gp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD42a, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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