Knockout Validation
(Knockout Validation: Lane 1: Wild-type K562 cell lysate; Lane 2: ALDH1B1 knockout K562 cell lysate; Predicted MW: 59kd Observed MW: 59kd Primary Ab: 1ug/ml Rabbit Anti-Human ALDH1B1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Human Aldehyde Dehydrogenase 1 Family, Member B1 (ALDH1B1) Polyclonal Antibody | anti-ALDH1B1 antibody
HRP-Linked Polyclonal Antibody to Aldehyde Dehydrogenase 1 Family, Member B1 (ALDH1B1)
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Knockout Validation
(Knockout Validation: Lane 1: Wild-type K562 cell lysate; Lane 2: ALDH1B1 knockout K562 cell lysate; Predicted MW: 59kd Observed MW: 59kd Primary Ab: 1ug/ml Rabbit Anti-Human ALDH1B1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Knockout Validation
(Knockout Validation: Lane 1: Wild-type K562 cell lysate; Lane 2: ALDH1B1 knockout K562 cell lysate; Predicted MW: 59kd Observed MW: 59kd Primary Ab: 1ug/ml Rabbit Anti-Human ALDH1B1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Uniprot Description
ALDH3B1: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid peroxidation. Belongs to the aldehyde dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.5; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - histidine; Amino Acid Metabolism - phenylalanine
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: cytoplasm; plasma membrane; cytosol; vesicle
Molecular Function: aldehyde dehydrogenase [NAD(P)+] activity; 3-chloroallyl aldehyde dehydrogenase activity
Biological Process: aldehyde catabolic process; ethanol catabolic process; alcohol metabolic process; lipid metabolic process
Research Articles on ALDH1B1
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Product Notes
The ALDH1B1 aldh3b1 (Catalog #AAA2110338) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HRP-Linked Polyclonal Antibody to Aldehyde Dehydrogenase 1 Family, Member B1 (ALDH1B1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Aldehyde Dehydrogenase 1 Family, Member B1 (ALDH1B1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ALDH1B1 aldh3b1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RPE827Hu01 -Recombina nt Aldehyde Dehydrogen ase 1 Family, Member B1 (ALDH1B1). It is sometimes possible for the material contained within the vial of "Aldehyde Dehydrogenase 1 Family, Member B1 (ALDH1B1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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