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Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) Recombinant Protein | CACNa1D recombinant protein

Recombinant Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D)

Gene Names
CACNA1D; CACH3; CACN4; PASNA; SANDD; Cav1.3; CCHL1A2; CACNL1A2
Applications
SDS-Page, Western Blot
Purity
> 90%
Synonyms
Calcium Channel; Voltage Dependent; L-Type; Alpha 1D Subunit (CACNa1D); Recombinant Calcium Channel; CACH3; CACN4; CACNL1A2; CCHL1A2; Cav1.3; Voltage-gated calcium channel subunit alpha Cav1.3; Calcium channel; L type; alpha-1 polypeptide; isoform 2; CACNa1D recombinant protein
Ordering
For Research Use Only!
Host
Host: E Coli
Source: Prokaryotic Expression
Purity/Purification
> 90%
Form/Format
Freeze-Dried Powder; 20mM Tris, 150mM NaCl, pH8.0, Containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Sequence Positions
Met1~Lys163
Sequence Length
2137
Applicable Applications for CACNa1D recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Species
Human
Tag
N-terminal His and GST-Tag
Isoelectric Point
10.6
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Membrane
Reconstitution
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
776
Molecular Weight
Predicted MW: 48.1kDa
Accurate MW: 48kDa
NCBI Official Full Name
calcium channel voltage-dependent L type alpha 1D subunit
NCBI Official Synonym Full Names
calcium voltage-gated channel subunit alpha1 D
NCBI Official Symbol
CACNA1D
NCBI Official Synonym Symbols
CACH3; CACN4; PASNA; SANDD; Cav1.3; CCHL1A2; CACNL1A2
NCBI Protein Information
voltage-dependent L-type calcium channel subunit alpha-1D

NCBI Description

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Research Articles on CACNa1D

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Product Notes

The CACNa1D (Catalog #AAA2105532) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1~Lys163. AAA Biotech's Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the CACNa1D for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcium Channel, Voltage Dependent, L-Type, Alpha 1D Subunit (CACNa1D), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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