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Angiotensin II Receptor Associated Protein (AGTRAP) Recombinant Protein | AGTRAP recombinant protein

Recombinant Angiotensin II Receptor Associated Protein (AGTRAP)

Gene Names
Agtrap; AT1R; Atrap; D4Wsu124e; 3300002E14Rik
Applications
SDS-Page, Western Blot
Purity
> 90%
Synonyms
Angiotensin II Receptor Associated Protein (AGTRAP); Recombinant Angiotensin II Receptor Associated Protein (AGTRAP); ATRAP; Type-1 angiotensin II receptor-associated protein; AT1 receptor-associated protein; AGTRAP recombinant protein
Ordering
For Research Use Only!
Host
Host: E Coli
Source: Prokaryotic Expression
Purity/Purification
> 90%
Form/Format
Freeze-Dried Powder; PBS, pH7.4, Containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Sequence Positions
Met1~Pro158
Sequence Length
161
Applicable Applications for AGTRAP recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
Species
Mouse
Tag
N-terminal His and GST-Tag
Isoelectric Point
5.4
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Membrane
Reconstitution
Reconstitute in PBS or others.
Preparation and Storage
Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months. Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for AGTRAP recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted MW: 47.3kDa
Accurate MW: 47kDa
NCBI Official Full Name
Agtrap protein
NCBI Official Synonym Full Names
angiotensin II, type I receptor-associated protein
NCBI Official Symbol
Agtrap
NCBI Official Synonym Symbols
AT1R; Atrap; D4Wsu124e; 3300002E14Rik
NCBI Protein Information
type-1 angiotensin II receptor-associated protein
UniProt Protein Name
Type-1 angiotensin II receptor-associated protein
UniProt Gene Name
Agtrap
UniProt Synonym Gene Names
Atrap
UniProt Entry Name
ATRAP_MOUSE

Uniprot Description

AGTRAP: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Endoplasmic reticulum; Membrane protein, multi-pass

Cellular Component: nucleoplasm; Golgi apparatus; membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; plasma membrane; integral to membrane; cell cortex; cytoplasmic vesicle

Molecular Function: protein binding; angiotensin type II receptor activity

Biological Process: regulation of blood pressure

Research Articles on AGTRAP

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Product Notes

The AGTRAP agtrap (Catalog #AAA2105400) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1~Pro158. AAA Biotech's Angiotensin II Receptor Associated Protein (AGTRAP) can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB). Researchers should empirically determine the suitability of the AGTRAP agtrap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiotensin II Receptor Associated Protein (AGTRAP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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