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Human Disrupted In Schizophrenia 1 (DISC1) Antibody Pair Kit | DISC1 antibody pair kit

Human Disrupted In Schizophrenia 1 (DISC1) Antibody Pair Kit (with Standard)

Reactivity
Human
Applications
ELISA, ELISA
Synonyms
Disrupted In Schizophrenia 1 (DISC1); Human Disrupted In Schizophrenia 1 (DISC1) Antibody Pair Kit (with Standard); SCZD9; DISC1 antibody pair kit
Ordering
For Research Use Only!
Reactivity
Human
Applicable Applications for DISC1 antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
Samples
Serum, Plasma, Tissue Homogenates, Cell Lysates, Cell Culture Supernates and Other Biological Fluids
Detection Range
31.2-2000ng/mL
Standard
Recombinant DISC1 (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
Product Categories/Family for DISC1 antibody pair kit

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
22,198 Da
NCBI Official Full Name
disrupted in schizophrenia 1
UniProt Protein Name
Disrupted in schizophrenia 1 protein
UniProt Gene Name
DISC1
UniProt Synonym Gene Names
KIAA0457

Uniprot Description

Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.

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Product Notes

The Human DISC1 disc1 (Catalog #AAA2101481) is an Antibody Pair Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2101481 Antibody Pair Kit recognizes Human DISC1. AAA Biotech's Disrupted In Schizophrenia 1 (DISC1) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex. Researchers should empirically determine the suitability of the DISC1 disc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Disrupted In Schizophrenia 1 (DISC1), Antibody Pair Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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