Typical Testing Data/Standard Curve (for reference only)
Human SPARC Related Modular Calcium Binding Protein 1 (SMOC1) ELISA Kit | SMOC1 elisa kit
Human SPARC Related Modular Calcium Binding Protein 1 (SMOC1) ELISA Kit
No significant cross-reactivity or interference between SPARC Related Modular Calcium Binding Protein 1 (SMOC1) and analogues was observed.
To minimize extra influence on the performance, operation procedures and lab conditions, especially room temperature, air humidity, incubator temperature should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same operator from the beginning to the end.
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a multi-domain secreted protein that may have a critical role in ocular and limb development. Mutations in this gene are associated with microphthalmia and limb anomalies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Uniprot Description
SMOC1: Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation. Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS). A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14q24.2
Cellular Component: basement membrane
Molecular Function: calcium ion binding; protein binding
Biological Process: cell differentiation; eye development; limb development; regulation of osteoblast differentiation; signal transduction
Disease: Microphthalmia With Limb Anomalies
Research Articles on SMOC1
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Product Notes
The Human SMOC1 smoc1 (Catalog #AAA2098133) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2098133 ELISA Kit recognizes Human SMOC1. It is sometimes possible for the material contained within the vial of "SPARC Related Modular Calcium Binding Protein 1 (SMOC1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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