Rabbit anti-Human Proteasome Activator Subunit 3 (PSME3) Polyclonal Antibody | anti-PSME3 antibody
Biotin-Linked Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3)
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Synonyms
Proteasome Activator Subunit 3 (PSME3); Polyclonal Antibody; Biotin-Linked Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3); Ki; PA28G; REG-GAMMA; 11S regulator complex subunit gamma; Activator of multicatalytic protease subunit 3; Ki nuclear autoantigen; Proteasome activator 28 subunit gamma; anti-PSME3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
500ug/ml (varies by lot)
Sequence Length
254
Applicable Applications for anti-PSME3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Conjugation
Biotin
Cross Reactivity
Human
Immunogen
PSME3 (Val7~Tyr254)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
29,506 Da
NCBI Official Full Name
proteasome activator subunit 3
NCBI Official Symbol
PSME3
NCBI Protein Information
proteasome activator complex subunit 3
UniProt Protein Name
Proteasome activator complex subunit 3
Protein Family
UniProt Gene Name
PSME3
UniProt Synonym Gene Names
PA28g; PA28gamma
Uniprot Description
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition ().
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Product Notes
The PSME3 psme3 (Catalog #AAA2096136) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Proteasome Activator Subunit 3 (PSME3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Proteasome Activator Subunit 3 (PSME3) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PSME3 psme3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Proteasome Activator Subunit 3 (PSME3), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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