Mediator Complex Subunit 6 (MED6) Recombinant Protein | MED6 recombinant protein

Recombinant Mediator Complex Subunit 6 (MED6)

Cat. Num. AAA2086878

• Gene Names: MED6; ARC33; NY-REN-28
• Applications: SDS-Page, Western Blot
• Purity: > 90%
• Synonyms: Mediator Complex Subunit 6 (MED6); Recombinant Mediator Complex Subunit 6 (MED6); NY-REN-28; ARC33; Activator-recruited cofactor 33 kDa component; Renal carcinoma antigen NY-REN-28; Mediator of RNA polymerase II transcription subunit 6; MED6 recombinant protein

• Host: E Coli
• Purity/Purification: > 90%
• Form/Format: Freeze-dried powder
• Sequence Length: 253

• Applicable Applications for MED6 recombinant protein: Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
• Fragment: Met1~Ala235
• Tag: N-terminal His-tag
• Buffer Formulation: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Source Note: Prokaryotic expression
• Organism Species: Human
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Isoelectric Point: 7
• Subcellular Location: Nucleus.
• Usage: Reconstitute in PBS or others.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

Product Categories/Family for MED6 recombinant protein

Recombinant Protein

NCBI and Uniprot Product Information

• NCBI GI #: 545746283
• NCBI GeneID: 10001
• NCBI Accession #: NP_001271138.1
• NCBI GenBank Nucleotide #: NM_001284209.1
• UniProt Accession #: O75586; O15401; Q53FE3; Q53HJ3; Q6FHQ4; Q9BTH1; Q9UHL1; B4DU17; B4E2P0
• Molecular Weight: 30.8kDa
• NCBI Official Full Name: mediator of RNA polymerase II transcription subunit 6 isoform 1
• NCBI Official Synonym Full Names: mediator complex subunit 6
• NCBI Official Symbol: MED6
• NCBI Official Synonym Symbols: ARC33; NY-REN-28
• NCBI Protein Information: mediator of RNA polymerase II transcription subunit 6
• UniProt Protein Name: Mediator of RNA polymerase II transcription subunit 6
• Protein Family: Mediator of RNA polymerase II transcription
• UniProt Gene Name: MED6
• UniProt Synonym Gene Names: ARC33; ARC33; hMed6

Uniprot Description

MED6: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 6 family.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 14q24.2

Cellular Component: membrane; nucleoplasm; nucleus; Srb-mediator complex

Molecular Function: protein binding; transcription coactivator activity; transcription factor binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcriptional preinitiation complex assembly