Rabbit anti-Human A Kinase Anchor Protein 12 (AKAP12) Polyclonal Antibody | anti-AKAP12 antibody
APC/CY7-Linked Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12)
Gene Names
Akap12; Srcs5; SSeCKS; Tsga12; AI317366
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
A Kinase Anchor Protein 12 (AKAP12); Polyclonal Antibody; APC/CY7-Linked Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12); AKAP250; Gravin; A-kinase anchor protein 250 kDa; Myasthenia gravis autoantigen; anti-AKAP12 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-AKAP12 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
AKAP12 (Pro1485~Ser1782)
Conjugation
APC-Cy7
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032838
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
169,743 Da
NCBI Official Full Name
A-kinase anchor protein 12
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein (gravin) 12
NCBI Official Symbol
Akap12
NCBI Official Synonym Symbols
Srcs5; SSeCKS; Tsga12; AI317366
NCBI Protein Information
A-kinase anchor protein 12
UniProt Protein Name
A-kinase anchor protein 12
Protein Family
UniProt Gene Name
Akap12
UniProt Synonym Gene Names
Gag12; Ssecks; AKAP-12; SSeCKS
Uniprot Description
AKAP12: a scaffold protein that contains 3 conserved PKA binding motifs. Suppresses podosome formation, inhibits RhoA and Cdc42 activity, and inhibits v-Src-induced oncogenic growth in NIH3T3. May inhibit Src-induced oncogenesis by reestablishing actin-based non-invasive cytoskeletal architecture.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 10|10 A1
Cellular Component: cytoplasm; focal adhesion; plasma membrane
Molecular Function: adenylate cyclase binding; receptor signaling complex scaffold activity
Biological Process: positive regulation of cAMP biosynthetic process; signal transduction
Research Articles on AKAP12
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Product Notes
The AKAP12 akap12 (Catalog #AAA2075701) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC/CY7-Linked Polyclonal Antibody to A Kinase Anchor Protein 12 (AKAP12) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's A Kinase Anchor Protein 12 (AKAP12) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the AKAP12 akap12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "A Kinase Anchor Protein 12 (AKAP12), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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