RPL7A recombinant protein

RPL7A, 1-266aa, Human, His tag, E Coli (Denatured)

Cat. Num. AAA206009

• Gene Names: RPL7A; L7A; TRUP; SURF3
• Applications: SDS-Page
• Purity: > 85% by SDS-PAGE
• Synonyms: RPL7A; 1-266aa; Human; His tag; E Coli (Denatured); 60S ribosomal protein L7a; L7A; SuRF3; TRuP; RPL7A recombinant protein

• Host: E Coli
• Purity/Purification: > 85% by SDS-PAGE
• Form/Format: Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
• Concentration: 1 mg/ml (determined by Bradford assay) (varies by lot)
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMPKGKKA KGKKVAPAPA VVKKQEAKKV VNPLFEKRPK NFGIGQDIQP KRDLTRFVKW PRYIRLQRQR AILYKRLKVP PAINQFTQAL DRQTATQLLK LAHKYRPETK QEKKQRLLAR AEKKAAGKGD VPTKRPPVLR AGVNTVTTLV ENKKAQLVVI AHDVDPIELV VFLPALCRKM GVPYCIIKGK ARLGRLVHRK TCTTVAFTQV NSEDKGALAK LVEAIRTNYN DRYDEIRRHW GGNVLGPKSV ARIAKLEKAK AKELATKLG
• Sequence Length: 266

• Applicable Applications for RPL7A recombinant protein: SDS-PAGE
• Antigen Species: Human
• Tag Information: His-tag
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for RPL7A recombinant protein

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL7A is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. Recombinant human RPL7A protein, fused to His-tag at N-terminus, was expressed in E Coli.

Product Categories/Family for RPL7A recombinant protein

Epigenomics (Transcription & Translation)

References

Zheng,S.E.,et al. (2009) J. Cancer Res. Clin. Oncol. 135 (8), 1025-1031

NCBI and Uniprot Product Information

• NCBI GI #: 4506661
• NCBI GeneID: 6130
• NCBI Accession #: NP_000963
• NCBI GenBank Nucleotide #: NM_000972.2
• UniProt Accession #: P62424; P11518; Q5T8U4
• Molecular Weight: 32.4kDa (289aa)
• NCBI Official Full Name: 60S ribosomal protein L7a
• NCBI Official Synonym Full Names: ribosomal protein L7a
• NCBI Official Symbol: RPL7A
• NCBI Official Synonym Symbols: L7A; TRUP; SURF3
• NCBI Protein Information: 60S ribosomal protein L7a
• UniProt Protein Name: 60S ribosomal protein L7a
• Protein Family: 60S ribosomal protein
• UniProt Gene Name: RPL7A
• UniProt Synonym Gene Names: SURF-3; SURF3

NCBI Description

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]