SDS-Page
PF4V1 recombinant protein
PF4V1, 31-104aa, Human, His tag, E Coli
Gene Names
PF4V1; PF4A; CXCL4L1; CXCL4V1; PF4-ALT; SCYB4V1
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
PF4V1; 31-104aa; Human; His tag; E Coli; Platelet factor 4 variant; CXCL4L1; CXCL4V1; PF4-ALT; PF4A; SCYB4V1; PF4V1 recombinant protein
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT.
Concentration
0.25 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MGSFARAEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES
Sequence Length
104
Applicable Applications for PF4V1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for PF4V1 recombinant protein
PF4V1 belongs to the intercrine alpha (chemokine CxC) family. It is a inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis (in vitro). Binding to heparin is much weaker than in the close homolog PF4/CXCL4. Recombinant human PF4V1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for PF4V1 recombinant protein
References
Green CJ, Charles RS, et al. (1989). Mol Cell Biol. 9 (4):1445-51.; Eisman R, Surrey S, et al. (1990). Blood. 76 (2):336-44.; Struyf S, Burdick MD, et al. (2004). Circ Res. 95 (9):855-7.; Kuo JH, Chen YP, et al. (2013). J Biol Chem. 288 (19):13522-33.;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10.6 kDa (97aa) confirmed by MALDI-TOF
NCBI Official Full Name
platelet factor 4 variant
NCBI Official Synonym Full Names
platelet factor 4 variant 1
NCBI Official Symbol
PF4V1
NCBI Official Synonym Symbols
PF4A; CXCL4L1; CXCL4V1; PF4-ALT; SCYB4V1
NCBI Protein Information
platelet factor 4 variant
UniProt Protein Name
Platelet factor 4 variant
Protein Family
UniProt Gene Name
PF4V1
UniProt Synonym Gene Names
CXCL4V1; SCYB4V1
NCBI Description
The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015]
Uniprot Description
Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).
Research Articles on PF4V1
Similar Products
Product Notes
The PF4V1 pf4v1 (Catalog #AAA205547) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's PF4V1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the PF4V1 pf4v1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MGSFARAEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES. It is sometimes possible for the material contained within the vial of "PF4V1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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