Western Blot (WB)
(Western Blot: Sample: Lane1: Human Serum; Lane2: Human Lung Tissue; Lane3: Porcine Brain Tissue; Lane4: Rat Brain Tissue; Lane5: Mouse Brain Tissue.)
Rabbit anti-Human Collapsin Response Mediator Protein 1 Polyclonal Antibody | anti-CRMP1 antibody
Collapsin Response Mediator Protein 1 (CRMP1) Polyclonal Antibody
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Serum; Lane2: Human Lung Tissue; Lane3: Porcine Brain Tissue; Lane4: Rat Brain Tissue; Lane5: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human Serum; Lane2: Human Lung Tissue; Lane3: Porcine Brain Tissue; Lane4: Rat Brain Tissue; Lane5: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CRMP1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CRMP1, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Brain Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Brain Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Cerebrum Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Cerebrum Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
CRMP-1: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Cytoskeletal; Hydrolase
Chromosomal Location of Human Ortholog: 4p16.2
Cellular Component: cytosol; microtubule organizing center; midbody; spindle
Molecular Function: filamin binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding
Biological Process: axon guidance; microtubule cytoskeleton organization; negative regulation of actin filament binding; negative regulation of neuron projection development; nervous system development; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Research Articles on CRMP1
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Product Notes
The CRMP1 crmp1 (Catalog #AAA2032288) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Collapsin Response Mediator Protein 1 (CRMP1) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Collapsin Response Mediator Protein 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the CRMP1 crmp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collapsin Response Mediator Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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