Serum Amyloid A2 Recombinant Protein | SAA2 recombinant protein

Recombinant Serum Amyloid A2 (SAA2)

Cat. Num. AAA2031147

• Applications: SDS-Page, Western Blot
• Purity: > 95%
• Synonyms: Serum Amyloid A2; Recombinant Serum Amyloid A2 (SAA2); SAA2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
• Concentration: Original Concentration: 200 ug/mL (varies by lot)

• Applicable Applications for SAA2 recombinant protein: Positive Control; Immunogen; SDS-PAGE; WB.; ; (May be suitable for use in other assays to be determined by the end user.)
• Organism Species: Homo sapiens (Human)
• Source: Prokaryotic expression
• Residues: Arg19~Tyr122
• Tags: N-terminal His Tag
• Subcellular Location: Secreted
• Traits: Freeze-dried powder
• Predicted isoelectric point: 9.1
• Predicted Molecular Mass: 15.3kDa
• Accurate Molecular Mass: 15kDa as determined by SDS-PAGE reducing conditions.
• Usage: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles.; Store at 2-8ºC for one month.; Aliquot and store at -80ºC for 12 months.; ; Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 188497671
• NCBI GeneID: 6289
• NCBI Accession #: NP_110381.2
• NCBI GenBank Nucleotide #: NM_030754.4
• Molecular Weight: 9,184 Da
• NCBI Official Full Name: serum amyloid A-2 protein isoform a
• NCBI Official Synonym Full Names: serum amyloid A2
• NCBI Official Symbol: SAA2
• NCBI Protein Information: serum amyloid A-2 protein
• UniProt Protein Name: Serum amyloid A-2 protein
• Protein Family: Serum amyloid A-2 protein
• UniProt Gene Name: SAA2
• UniProt Synonym Gene Names: SAA2
• UniProt Entry Name: SAA2_HUMAN

Uniprot Description

SAA1: Major acute phase reactant. Apolipoprotein of the HDL complex. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function. Elevated serum SAA1 protein levels may be associated with lung cancer. Belongs to the SAA family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: extracellular region

Molecular Function: heparin binding; G-protein-coupled receptor binding

Biological Process: receptor-mediated endocytosis; platelet activation; neutrophil chemotaxis; positive regulation of cell adhesion; macrophage chemotaxis; positive regulation of interleukin-1 secretion; elevation of cytosolic calcium ion concentration; regulation of protein secretion; negative regulation of inflammatory response; acute-phase response; innate immune response; lymphocyte chemotaxis; positive regulation of cytokine secretion