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SDS-Page

Fc Fragment Of IgA Receptor Recombinant Protein | FcaR recombinant protein

Recombinant Fc Fragment Of IgA Receptor (FcaR)

Gene Names
FCAR; CD89; FcalphaRI; CTB-61M7.2
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
>95%
Synonyms
Fc Fragment Of IgA Receptor; Recombinant Fc Fragment Of IgA Receptor (FcaR); FcaR recombinant protein
Ordering
For Research Use Only!
Host
Host: E Coli
Source: Prokaryotic expression
Purity/Purification
>95%
Form/Format
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Concentration
8.8 (varies by lot)
Sequence
The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- TPEAFLYQLS LMKNSTQTVI EKKLGFQKEA EFIINHMNST LAGCYQCQYR KKNHWSEQSK PLKLVVTGLY DKPVLSTDQS LVLLPGENVS FKCSSAHNLF NRFSLAKEGE ASLPLHQHKE SQGNFHLGPV NADFIGKYRC YGWHNNSPYV WSAPSDALEL IVSVTSLDSE KHDYVMENSI RIGMAGLVLV ILLVIVSEDW YSHRISHKEC CQERAAKRWS KQGVRPSDCR
Sequence Length
239
Applicable Applications for FcaR recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Predicted Molecular Mass
29.7kDa
Accurate Molecular Mass (KD)
30kDa
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Expression System
Prokaryotic expression
Tag
two N-terminal Tags, His-tag and T7-tag
Organism Species
Rattus norvegicus (Rat)
Fragment
Thr51~Arg280
Usage
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
28,343 Da
NCBI Official Full Name
Fc fragment of IgA, receptor for, isoform CRA_f
NCBI Official Synonym Full Names
Fc fragment of IgA receptor
NCBI Official Symbol
FCAR
NCBI Official Synonym Symbols
CD89; FcalphaRI; CTB-61M7.2
NCBI Protein Information
immunoglobulin alpha Fc receptor
UniProt Protein Name
Immunoglobulin alpha Fc receptor
UniProt Gene Name
FCAR
UniProt Synonym Gene Names
CD89; IgA Fc receptor
UniProt Entry Name
FCAR_HUMAN

NCBI Description

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FCAR: Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: IgA binding

Biological Process: immune response

Research Articles on FcaR

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Product Notes

The FcaR fcar (Catalog #AAA2029321) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Fc Fragment Of IgA Receptor can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the FcaR fcar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.
MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGS- TPEAFLYQLS LMKNSTQTVI EKKLGFQKEA EFIINHMNST LAGCYQCQYR KKNHWSEQSK PLKLVVTGLY DKPVLSTDQS LVLLPGENVS FKCSSAHNLF NRFSLAKEGE ASLPLHQHKE SQGNFHLGPV NADFIGKYRC YGWHNNSPYV WSAPSDALEL IVSVTSLDSE KHDYVMENSI RIGMAGLVLV ILLVIVSEDW YSHRISHKEC CQERAAKRWS KQGVRPSDCR
. It is sometimes possible for the material contained within the vial of "Fc Fragment Of IgA Receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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