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Western Blot (WB) (Western Blot:Sample: Recombinant Tyk2, Mouse.)

Rabbit Tyrosine Kinase 2 Polyclonal Antibody | anti-Tyk2 antibody

Polyclonal Antibody to Tyrosine Kinase 2 (Tyk2)

Gene Names
Tyk2; JTK1
Reactivity
Mus musculus (Mouse)
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Tyrosine Kinase 2; Polyclonal Antibody; Polyclonal Antibody to Tyrosine Kinase 2 (Tyk2); anti-Tyk2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mus musculus (Mouse)
Clonality
Polyclonal
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-Tyk2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Immunoprecipitation (IP).
Application Notes
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Source
Polyclonal antibody preparation
Traits
Liquid
Immunogen
Recombinant Tyk2 (His667~Asp914) expressed in E.coli (MBS2029000).
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot:Sample: Recombinant Tyk2, Mouse.)

Western Blot (WB) (Western Blot:Sample: Recombinant Tyk2, Mouse.)

Western Blot (WB)

(Western Blot:Sample: Mouse Liver lysate;Primary Ab: 1ug/ml Rabbit Anti-Mouse Tyk2 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Western Blot (WB) (Western Blot:Sample: Mouse Liver lysate;Primary Ab: 1ug/ml Rabbit Anti-Mouse Tyk2 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin- embedded Kidney tissue))

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded Kidney tissue))

Immunohistochemistry (IHC)

(DAB staining on IHC-P;Samples: Mouse Testis Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P;Samples: Mouse Testis Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Non-receptor tyrosine-protein kinase TYK2
NCBI Official Synonym Full Names
tyrosine kinase 2
NCBI Official Symbol
Tyk2
NCBI Official Synonym Symbols
JTK1
NCBI Protein Information
non-receptor tyrosine-protein kinase TYK2
UniProt Protein Name
Non-receptor tyrosine-protein kinase TYK2
UniProt Gene Name
Tyk2

Uniprot Description

Tyk2: a non-receptor tyrosine-protein kinase of the JakA family. Activated in signaling from the IL-2, gp130 and IFN families of receptors. Phosphorylates the interferon-alpha/beta receptor alpha chain.

Protein type: EC 2.7.10.2; JakA family; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group

Chromosomal Location of Human Ortholog: 9|9 A3

Cellular Component: cytoplasm; cytoskeleton; extracellular exosome; extrinsic component of cytoplasmic side of plasma membrane; membrane; nucleus

Molecular Function: ATP binding; growth hormone receptor binding; kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein kinase activity; protein tyrosine kinase activity; receptor binding; transferase activity; type 1 angiotensin receptor binding

Biological Process: cell differentiation; cell migration; innate immune response; peptidyl-tyrosine autophosphorylation; phosphorylation; protein amino acid phosphorylation; regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on Tyk2

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Product Notes

The Tyk2 tyk2 (Catalog #AAA2026840) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Tyrosine Kinase 2 (Tyk2) reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Tyrosine Kinase 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunocytochemistry (ICC), Immunoprecipitation (IP). . Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the Tyk2 tyk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tyrosine Kinase 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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