Western Blot (WB)
(Western Blot: Sample: Porcine Adrenal gland lysate; Primary Ab: 1ug/ml Rabbit Anti-Human STAR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Human Steroidogenic Acute Regulatory Protein Polyclonal Antibody | anti-STAR antibody
Polyclonal Antibody to Steroidogenic Acute Regulatory Protein (STAR)
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Porcine Adrenal gland lysate; Primary Ab: 1ug/ml Rabbit Anti-Human STAR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Porcine Adrenal gland lysate; Primary Ab: 1ug/ml Rabbit Anti-Human STAR Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Human Tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]
Uniprot Description
STAR: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. May interact with TSPO. Expressed in gonads, adrenal cortex and kidney.
Protein type: Carrier; Lipid-binding; Mitochondrial
Chromosomal Location of Human Ortholog: 8p11.23
Cellular Component: cell soma; cytosol; mitochondrial crista; mitochondrial intermembrane space; neuron projection
Molecular Function: cholesterol binding; cholesterol transporter activity; protein binding
Biological Process: bile acid biosynthetic process; biphenyl metabolic process; brain development; C21-steroid hormone biosynthetic process; cellular response to alkaloid; cellular response to cadmium ion; cellular response to cAMP; cellular response to dexamethasone stimulus; cellular response to epinephrine stimulus; cellular response to fibroblast growth factor stimulus; cellular response to follicle-stimulating hormone stimulus; cellular response to glucose stimulus; cellular response to growth hormone stimulus; cellular response to insulin stimulus; cellular response to interferon-gamma; cellular response to luteinizing hormone stimulus; cellular response to transforming growth factor beta stimulus; cholesterol metabolic process; circadian sleep/wake cycle, REM sleep; dibenzo-p-dioxin metabolic process; diterpenoid metabolic process; estrogen biosynthetic process; glucocorticoid metabolic process; insecticide metabolic process; intracellular cholesterol transport; male gonad development; negative regulation of neuron apoptosis; phenol-containing compound metabolic process; phthalate metabolic process; positive regulation of gene expression; positive regulation of neurogenesis; regulation of neuronal synaptic plasticity; response to activity; response to corticosterone stimulus; response to drug; response to estrogen; response to ethanol; response to herbicide; response to hydrogen peroxide; response to ionizing radiation; response to lead ion; response to leptin; response to nicotine; response to nutrient; steroid biosynthetic process
Disease: Lipoid Congenital Adrenal Hyperplasia
Research Articles on STAR
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Product Notes
The STAR star (Catalog #AAA2026769) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Steroidogenic Acute Regulatory Protein (STAR) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Steroidogenic Acute Regulatory Protein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the STAR star for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Steroidogenic Acute Regulatory Protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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