Neuronal Pentraxin I (NPTX1) Recombinant Protein | NPTX1 recombinant protein

Recombinant Neuronal Pentraxin I (NPTX1)

Cat. Num. AAA2011250

• Gene Names: NPTX1; NP1
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Neuronal Pentraxin I (NPTX1); Recombinant Neuronal Pentraxin I (NPTX1); NPTX1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGSEF- NLEQY SRLNSSSQTN SLKDLLQSKI DELERQVLSR VNTLEEGKGG PRNDTEERVK IETALTSLHQ RISELEKGQK DNRPGDKFQL TFPLRTNYMY AKVKKSLPEM YAFTVCMWLK SSATPGVGTP FSYAVPGQAN ELVLIEWGNN PMEILINDKV AKLPFVINDG KWHHICVTWT TRDGVWEAYQ DGTQGGSGEN LAPYHPIKPQ GVLVLGQEQD TLGGGFDATQ AFVGELAHFN IWDR
• Sequence Length: 432

• Applicable Applications for NPTX1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Asn146~Arg384 (Accession # Q15818) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 55770878
• NCBI GeneID: 4884
• NCBI Accession #: NP_002513.2
• NCBI GenBank Nucleotide #: NM_002522.3
• UniProt Accession #: Q15818; Q5FWE6; B3KXH3
• Molecular Weight: 28.4kDa
• NCBI Official Full Name: neuronal pentraxin-1
• NCBI Official Synonym Full Names: neuronal pentraxin I
• NCBI Official Symbol: NPTX1
• NCBI Official Synonym Symbols: NP1
• NCBI Protein Information: neuronal pentraxin-1; NP-I
• UniProt Protein Name: Neuronal pentraxin-1
• Protein Family: Neuronal pentraxin
• UniProt Gene Name: NPTX1
• UniProt Synonym Gene Names: NP1; NP-I
• UniProt Entry Name: NPTX1_HUMAN

NCBI Description

NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

NPTX1: May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: transport vesicle; neuron projection; mitochondrion; plasma membrane

Molecular Function: metal ion binding

Biological Process: synaptic transmission; central nervous system development; transport; mitochondrial fragmentation during apoptosis; mitochondrial transport