Macrophage Inflammatory Protein 4 Alpha (MIP4a) Recombinant Protein | MIP4a recombinant protein

Recombinant Macrophage Inflammatory Protein 4 Alpha (MIP4a)

Cat. Num. AAA2010625

• Gene Names: CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Macrophage Inflammatory Protein 4 Alpha (MIP4a); Recombinant Macrophage Inflammatory Protein 4 Alpha (MIP4a); MIP4a recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and S-tag, its sequence is listed below.; MHHHHHHSSGLVPRGSGMKETAAAKFERQHMDSPDLGTDDDDKAMADIGS-TRGSDIS KTCCFQYSHK PLPWTWVRSY EFTSNSCSQR AVIFTTKRGK KVCTHPRKKW VQKYISLLKT PKQL
• Sequence Length: 94

• Applicable Applications for MIP4a recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Thr24~Leu94 (Accession # Q9Y258) with two N-terminal Tags, His-tag and S-tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

NCBI and Uniprot Product Information

• NCBI GI #: 5174671
• NCBI GeneID: 10344
• NCBI Accession #: NP_006063.1
• NCBI GenBank Nucleotide #: NM_006072.4
• UniProt Accession #: Q9Y258; Q52LV8; A0N0Q5
• Molecular Weight: 13.8kDa
• NCBI Official Full Name: C-C motif chemokine 26
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 26
• NCBI Official Symbol: CCL26
• NCBI Official Synonym Symbols: IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
• NCBI Protein Information: C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26
• UniProt Protein Name: C-C motif chemokine 26
• UniProt Gene Name: CCL26
• UniProt Synonym Gene Names: SCYA26; MIP-4-alpha; TSC-1
• UniProt Entry Name: CCL26_HUMAN

NCBI Description

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Chemokine

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; immune response; positive regulation of endothelial cell proliferation; signal transduction; chemotaxis; inflammatory response; positive regulation of cell migration