SDS-Page
Kidney Injury Molecule 1 (Kim1) Recombinant Protein | Kim1 recombinant protein
Recombinant Kidney Injury Molecule 1 (Kim1)
Gene Names
Havcr1; Tim1; KIM-1; TIM-1; Timd1; AI503787
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
> 95%
Synonyms
Kidney Injury Molecule 1 (Kim1); Recombinant Kidney Injury Molecule 1 (Kim1); Kim1 recombinant protein
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSG SEF-YVEVKGV VGHPVTLPCT YSTYRGITTT CWGRGQCPSS ACQNTLIWTN GHRVTYQKSS RYNLKGHISE GDVSLTIENS VESDSGLYCC RVEIPGWFND QKVTFSLQVK PEIPTRPPTR PTTTRPTATG RPTTISTRST HVPTSIRVST STPPTSTHTW THKPEPTTFC PHETTAEVTG IPSHTPTDWN GTVTSSGDTW SNHTEAIPPG KPQKNPTKG
MGHHHHHHSG SEF-YVEVKGV VGHPVTLPCT YSTYRGITTT CWGRGQCPSS ACQNTLIWTN GHRVTYQKSS RYNLKGHISE GDVSLTIENS VESDSGLYCC RVEIPGWFND QKVTFSLQVK PEIPTRPPTR PTTTRPTATG RPTTISTRST HVPTSIRVST STPPTSTHTW THKPEPTTFC PHETTAEVTG IPSHTPTDWN GTVTSSGDTW SNHTEAIPPG KPQKNPTKG
Sequence Length
282
Applicable Applications for Kim1 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Organism
Mus musculus (Mouse)
Expression System
Prokaryotic expression
Residues
Tyr22~Gly237 (Accession # Q5QNS5) with N-terminal His-Tag
Subcellular Location
Membrane; Single-pass type I membrane protein
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Predicted Isoelectric Point
8.7
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25.2kDa
NCBI Official Full Name
hepatitis A virus cellular receptor 1 homolog isoform b
NCBI Official Synonym Full Names
hepatitis A virus cellular receptor 1
NCBI Official Symbol
Havcr1
NCBI Official Synonym Symbols
Tim1; KIM-1; TIM-1; Timd1; AI503787
NCBI Protein Information
hepatitis A virus cellular receptor 1 homolog; TIMD-1; HAVcr-1; kidney injury molecule 1; t cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin and mucin domain containing 1; t cell immunoglobulin and mucin domain-containing protein 1
UniProt Protein Name
Hepatitis A virus cellular receptor 1 homolog
UniProt Gene Name
Havcr1
UniProt Synonym Gene Names
Kim1; Tim1; Timd1; HAVcr-1; KIM-1; TIMD-1; TIM-1
UniProt Entry Name
HAVR1_MOUSE
Uniprot Description
TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: protein binding
Biological Process: positive regulation of mast cell activation
Research Articles on Kim1
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Product Notes
The Kim1 havcr1 (Catalog #AAA2010115) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Kidney Injury Molecule 1 (Kim1) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the Kim1 havcr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF-YVEVKG V VGHPVTLPCT YSTYRGITTT CWGRGQCPSS ACQNTLIWTN GHRVTYQKSS RYNLKGHISE GDVSLTIENS VESDSGLYCC RVEIPGWFND QKVTFSLQVK PEIPTRPPTR PTTTRPTATG RPTTISTRST HVPTSIRVST STPPTSTHTW THKPEPTTFC PHETTAEVTG IPSHTPTDWN GTVTSSGDTW SNHTEAIPPG KPQKNPTKG. It is sometimes possible for the material contained within the vial of "Kidney Injury Molecule 1 (Kim1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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