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KLF7 cdna clone

KLF7

Gene Names
KLF7; UKLF
Synonyms
KLF7; UKLF; KLF7 cdna clone
Ordering
For Research Use Only!
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGGACGTGTTGGCTAGTTATAGTATATTCCAGGAGCTACAACTTGTCCACGACACCGGCTACTTCTCAGCTTTACCATCCCTGGAGGAGACCTGGCAGCAGACATGCCTTGAATTGGAACGCTACCTACAGACGGAGCCCCGGAGGATCTCAGAGACCTTTGGTGAGGACTTGGACTGTTTCCTCCACGCTTCCCCTCCCCCGTGCATTGAGGAAAGCTTCCGTCGCTTAGACCCCCTGCTGCTCCCCGTGGAAGCGGCCATCTGTGAGAAGAGCTCGGCAGTGGACATCTTGCTCTCTCGGGACAAGTTGCTATCTGAGACCTGCCTCAGCCTCCAGCCGGCCAGCTCTTCTCTAGACAGCTACACAGCCGTCAACCAGGCCCAGCTCAACGCAGTGACCTCATTAACGCCCCCATCGTCCCCTGAGCTCAGCCGCCATCTGGTCAAAACCTCACAAACTCTCTCTGCCGTGGATGGCACGGTGACGTTGAAACTGGTGGCCAAGAAGGCTGCTCTCAGCTCCGTAAAGGTGGGAGGGGTCGCAACAGCTGCAGCAGCCGTGACGGCTGCGGGGGCCGTTAAGAGTGGACAGAGCGACAGTGACCAAGGAGGGCTAGGGGCTGAAGCATGTCCCGAAAACAAGAAGAGGGTTCACCGCTGTCAGTTTAACGGGTGCCGGAAAGTTTATACAAAAAGCTCCCACTTAAAGGCCCACCAGAGGACTCACACAGGTGAGAAGCCTTATAAGTGCTCATGGGAGGGATGTGAGTGGCGTTTTGCACGAAGCGATGAGCTCACGAGGCACTACAGGAAACACACAGGTGCAAAGCCCTTCAAATGCAACCACTGCGACAGGTGTTTTTCCAGGTCTGACCATCTTGCCCTCCACATGAAGAGACATATCTAA

Translation Sequence: MDVLASYSIF QELQLVHDTG YFSALPSLEE TWQQTCLELE RYLQTEPRRI SETFGEDLDCFLHASPPPCI EESFRRLDPL LLPVEAAICE KSSAVDILLS RDKLLSETCL SLQPASSSLDSYTAVNQAQL NAVTSLTPPS SPELSRHLVK TSQTLSAVDG TVTLKLVAKK AALSSVKVGGVATAAAAVTA AGAVKSGQSD SDQGGLGAEA CPENKKRVHR CQFNGCRKVY TKSSHLKAHQRTHTGEKPYK CSWEGCEWRF ARSDELTRHY RKHTGAKPFK CNHCDRCFSR SDHLALHMKRHI
Sequence Length
302
Species
Human
Chromosome Location
2q32
OMIM Reference Number
604865
cDNA Size
909bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for KLF7 cdna clone
KLF7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. A pseudogene of KLF7 is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
Product Categories/Family for KLF7 cdna clone

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
Krueppel-like factor 7 isoform 1
NCBI Official Synonym Full Names
Kruppel like factor 7
NCBI Official Symbol
KLF7
NCBI Official Synonym Symbols
UKLF
NCBI Protein Information
Krueppel-like factor 7
UniProt Protein Name
Krueppel-like factor 7
Protein Family
UniProt Gene Name
KLF7
UniProt Synonym Gene Names
UKLF
UniProt Entry Name
KLF7_HUMAN

NCBI Description

The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Description

KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 2q32

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis

Research Articles on KLF7

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Product Notes

The KLF7 klf7 (Catalog #AAA201005) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGACGTGT TGGCTAGTTA TAGTATATTC CAGGAGCTAC AACTTGTCCA CGACACCGGC TACTTCTCAG CTTTACCATC CCTGGAGGAG ACCTGGCAGC AGACATGCCT TGAATTGGAA CGCTACCTAC AGACGGAGCC CCGGAGGATC TCAGAGACCT TTGGTGAGGA CTTGGACTGT TTCCTCCACG CTTCCCCTCC CCCGTGCATT GAGGAAAGCT TCCGTCGCTT AGACCCCCTG CTGCTCCCCG TGGAAGCGGC CATCTGTGAG AAGAGCTCGG CAGTGGACAT CTTGCTCTCT CGGGACAAGT TGCTATCTGA GACCTGCCTC AGCCTCCAGC CGGCCAGCTC TTCTCTAGAC AGCTACACAG CCGTCAACCA GGCCCAGCTC AACGCAGTGA CCTCATTAAC GCCCCCATCG TCCCCTGAGC TCAGCCGCCA TCTGGTCAAA ACCTCACAAA CTCTCTCTGC CGTGGATGGC ACGGTGACGT TGAAACTGGT GGCCAAGAAG GCTGCTCTCA GCTCCGTAAA GGTGGGAGGG GTCGCAACAG CTGCAGCAGC CGTGACGGCT GCGGGGGCCG TTAAGAGTGG ACAGAGCGAC AGTGACCAAG GAGGGCTAGG GGCTGAAGCA TGTCCCGAAA ACAAGAAGAG GGTTCACCGC TGTCAGTTTA ACGGGTGCCG GAAAGTTTAT ACAAAAAGCT CCCACTTAAA GGCCCACCAG AGGACTCACA CAGGTGAGAA GCCTTATAAG TGCTCATGGG AGGGATGTGA GTGGCGTTTT GCACGAAGCG ATGAGCTCAC GAGGCACTAC AGGAAACACA CAGGTGCAAA GCCCTTCAAA TGCAACCACT GCGACAGGTG TTTTTCCAGG TCTGACCATC TTGCCCTCCA CATGAAGAGA CATATCTAA< br> Tra nslation Sequence: MDVLASYSIF QELQLVHDTG YFSALPSLEE TWQQTCLELE RYLQTEPRRI SETFGEDLDC FLHASPPPCI EESFRRLDPL LLPVEAAICE KSSAVDILLS RDKLLSETCL SLQPASSSLD SYTAVNQAQL NAVTSLTPPS SPELSRHLVK TSQTLSAVDG TVTLKLVAKK AALSSVKVGG VATAAAAVTA AGAVKSGQSD SDQGGLGAEA CPENKKRVHR CQFNGCRKVY TKSSHLKAHQ RTHTGEKPYK CSWEGCEWRF ARSDELTRHY RKHTGAKPFK CNHCDRCFSR SDHLALHMKR HI. It is sometimes possible for the material contained within the vial of "KLF7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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