Western Blot (WB)
(Western Blot: Sample: Recombinant UCN3, Human.)
Rabbit anti-Human Urocortin 3 (UCN3) Polyclonal Antibody | anti-UCN3 antibody
Polyclonal Antibody to Urocortin 3 (UCN3)
MGHHHHHHSGSEF-LPHKFYKAK PIFSCLNTAL SEAEKGQWED ASLLSKRSFH YLRSRDASSG EEEEGKEKKT FPISGARGGA RGTRYRYVSQ AQPRGKPRQD TAKSPHRTKF TLSLDVPTNI MNLLFNIAKA KNLRAQAAAN AHLMAQIGRK K
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant UCN3, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant UCN3, Human.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:HumanTissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016]
Uniprot Description
UCN3: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10p15.1
Cellular Component: axon terminus; extracellular region; extracellular space; intracellular
Molecular Function: corticotropin-releasing hormone receptor 2 binding; G-protein coupled receptor binding; hormone activity
Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; cellular response to nutrient levels; digestion; positive regulation of insulin secretion; positive regulation of membrane potential; response to corticosterone stimulus; response to glucose stimulus; response to starvation
Research Articles on UCN3
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Product Notes
The UCN3 ucn3 (Catalog #AAA2007298) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Urocortin 3 (UCN3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Urocortin 3 (UCN3) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the UCN3 ucn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-LPHKFY KAK PIFSCLNTAL SEAEKGQWED ASLLSKRSFH YLRSRDASSG EEEEGKEKKT FPISGARGGA RGTRYRYVSQ AQPRGKPRQD TAKSPHRTKF TLSLDVPTNI MNLLFNIAKA KNLRAQAAAN AHLMAQIGRK K. It is sometimes possible for the material contained within the vial of "Urocortin 3 (UCN3), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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