Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Sphingosine 1 Phosphate Lyase 1 (SGPL1) Antibody | anti-SGPL1 antibody
Polyclonal Antibody to Sphingosine 1 Phosphate Lyase 1 (SGPL1)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.
Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver TissuePrimary Ab: 20ug/ml Rabbit Anti-Human SGPL1 AntibodySecond Ab: 2µg/mL HRP-Linked CaprineAnti-Rabbit IgG Polyclonal Antibody(Catalog:MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Liver TissuePrimary Ab: 20ug/ml Rabbit Anti-Human SGPL1 AntibodySecond Ab: 2µg/mL HRP-Linked CaprineAnti-Rabbit IgG Polyclonal Antibody(Catalog:MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Colon TissuePrimary Ab: 20ug/ml Rabbit Anti-Human SGPL1 Antibody Second Ab: 2µg/mL HRP-Linked CaprineAnti-Rabbit IgG Polyclonal Antibody(Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Colon TissuePrimary Ab: 20ug/ml Rabbit Anti-Human SGPL1 Antibody Second Ab: 2µg/mL HRP-Linked CaprineAnti-Rabbit IgG Polyclonal Antibody(Catalog: MBS2086047))
NCBI and Uniprot Product Information
Uniprot Description
SGPL1: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily.
Protein type: Apoptosis; EC 4.1.2.27; Lipid Metabolism - sphingolipid; Lyase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 10q22.1
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral component of endoplasmic reticulum membrane
Molecular Function: carboxy-lyase activity; protein binding; pyridoxal phosphate binding; sphinganine-1-phosphate aldolase activity
Biological Process: androgen metabolic process; ceramide metabolic process; estrogen metabolic process; fatty acid metabolic process; hemopoiesis; kidney development; Leydig cell differentiation; luteinization; palate development; platelet-derived growth factor receptor signaling pathway; post-embryonic development; regulation of multicellular organism growth; skeletal morphogenesis; spermatogenesis; sphingolipid biosynthetic process; sphingolipid catabolic process; vasculogenesis
Disease: Nephrotic Syndrome 14
Research Articles on SGPL1
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Product Notes
The SGPL1 sgpl1 (Catalog #AAA2006235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Sphingosine 1 Phosphate Lyase 1 (SGPL1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Sphingosine 1 Phosphate Lyase 1 (SGPL1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC-P) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the SGPL1 sgpl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sphingosine 1 Phosphate Lyase 1 (SGPL1), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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