Western Blot (WB)
(Western Blot: Sample: Human MCF7 Cells.)
Rabbit anti-Mouse Matrix Metalloproteinase 11 (MMP11) Polyclonal Antibody | anti-MMP11 antibody
Polyclonal Antibody to Matrix Metalloproteinase 11 (MMP11)
MGHHHHHHSGSEF-ALLE PETPPDVCET SFDAVSTIRG ELFFFKAGFV WRLRSGRLQP GYPALASRHW QGLPSPVDAA FEDAQGQIWF FQGAQYWVYD GEKPVLGPAP LSKLGLQGSP VHAALVWGPE KNKIYFFRGG DYWRFHPRTQ RVDNPVPRRS TDWRGVPSEI DAAFQDAEGY AYFLRGHLYW KFDPVKVKVL EGFPRPVGPD FFDCAEPANT F
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Human MCF7 Cells.)
Western Blot (WB)
(Western Blot: Sample: Human MCF7 Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant MMP11, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant MMP11, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Ovary Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Uterus Tissue.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the matrix metalloproteinase family of endopeptidases that are involved in remodeling extracellular matrix during, for example, embryonic development and tumor progression. The encoded protein undergoes post-translational proteolytic processing by furin endopeptidase to form an active enzyme. Subcutaneous introduction of cells expressing the encoded protein into nude mice results in increased tumor incidence. Mice lacking the encoded protein exhibit a decreased incidence of chemically-induced tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Uniprot Description
MMP11: May play an important role in the progression of epithelial malignancies. Belongs to the peptidase M10A family.
Protein type: EC 3.4.24.-; Extracellular matrix; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10 C1|10 38.62 cM
Cellular Component: extracellular matrix; extracellular region; proteinaceous extracellular matrix
Molecular Function: hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding
Biological Process: collagen catabolic process; collagen fibril organization; extracellular matrix organization; multicellular organism development; negative regulation of fat cell differentiation; proteolysis
Research Articles on MMP11
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Product Notes
The MMP11 mmp11 (Catalog #AAA2006181) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Matrix Metalloproteinase 11 (MMP11) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Matrix Metalloproteinase 11 (MMP11) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the MMP11 mmp11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSG SEF-ALLE PETPPDVCET SFDAVSTIRG ELFFFKAGFV WRLRSGRLQP GYPALASRHW QGLPSPVDAA FEDAQGQIWF FQGAQYWVYD GEKPVLGPAP LSKLGLQGSP VHAALVWGPE KNKIYFFRGG DYWRFHPRTQ RVDNPVPRRS TDWRGVPSEI DAAFQDAEGY AYFLRGHLYW KFDPVKVKVL EGFPRPVGPD FFDCAEPANT F. It is sometimes possible for the material contained within the vial of "Matrix Metalloproteinase 11 (MMP11), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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