Western Blot (WB)
(Western Blot: Sample: Porcine Liver lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse Hpt Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Mouse Haptoglobin (Hpt) Polyclonal Antibody | anti-Hpt antibody
Polyclonal Antibody to Haptoglobin (Hpt)
MGHHHHHHSGSEF- AKM ISRHGLTTGA TLISDQWLLT TAKNLFLNHS ETASAKDITP TLTLYVGKNQ LVEIEKVVLH PNHSVVDIGL IKLKQRVLVT ERVMPICLPS KDYIAPGRVG YVSGWGRNAN FRFTDRLKYV MLPVADQDKC VVHYENSTVP EKKNLTSPVG VQPILNEHTF C
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Porcine Liver lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse Hpt Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Porcine Liver lysate; Primary Ab: 3ug/ml Rabbit Anti-Mouse Hpt Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a plasma glycoprotein called haptoglobin that binds free hemoglobin. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta subunits that form a disulfide-linked tetrameric protein that plays an important role in the sequestration and clearance of extracorpuscular hemoglobin. Mice lacking the encoded protein exhibit stunted development of lymphoid organs associated with lower counts of mature T and B cells in the blood and secondary lymphoid compartments. [provided by RefSeq, Aug 2016]
Uniprot Description
HPR: a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 8 D3|8 57.11 cM
Cellular Component: endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus
Molecular Function: antioxidant activity; hemoglobin binding; protein homodimerization activity; serine-type endopeptidase activity
Biological Process: acute-phase response; defense response to bacterium; immune system process; liver development; negative regulation of oxidoreductase activity; Notch signaling pathway; proteolysis; response to hydrogen peroxide
Research Articles on Hpt
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Product Notes
The Hpt hp (Catalog #AAA2004632) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Haptoglobin (Hpt) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Haptoglobin (Hpt) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the Hpt hp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- AKM ISRHGLTTGA TLISDQWLLT TAKNLFLNHS ETASAKDITP TLTLYVGKNQ LVEIEKVVLH PNHSVVDIGL IKLKQRVLVT ERVMPICLPS KDYIAPGRVG YVSGWGRNAN FRFTDRLKYV MLPVADQDKC VVHYENSTVP EKKNLTSPVG VQPILNEHTF C. It is sometimes possible for the material contained within the vial of "Haptoglobin (Hpt), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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