Western Blot (WB)
(Western Blot: Sample: Rat Heart lysate; Primary Ab: 1ug/ml Rabbit Anti-Rat PARK7 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Rat Parkinson Disease Protein 7 (PARK7) Polyclonal Antibody | anti-PARK7 antibody
Polyclonal Antibody to Parkinson Disease Protein 7 (PARK7)
MGHHHHHHSGSEF-MASKRALVIL AKGAEEMETV IPVDIMRRAG IKVTVAGLAG KDPVQCSRDV VICPDTSLEE AKTQGPYDVV VLPGGNLGAQ NLSESALVKE ILKEQENRKG LIAAICAGPT ALLAHEVGFG CKVTSHPLAK DKMMNGSHYS YSESRVEKDG LILTSRGPGT SFEFALAIVE ALSGKDMANQ VKAPLVLKD
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Rat Heart lysate; Primary Ab: 1ug/ml Rabbit Anti-Rat PARK7 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Rat Heart lysate; Primary Ab: 1ug/ml Rabbit Anti-Rat PARK7 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Kidney tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Kidney tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue))
NCBI and Uniprot Product Information
NCBI Description
displays a specific localization pattern to the anterior-ventral surface of the equatorial segment; may play a role in sperm-egg interactions and fertilization [RGD, Feb 2006]
Uniprot Description
DJ-1: associated with autosomal recessive early onset parkinsonism. Involved in the oxidative stress response. Three cysteines in DJ-1 may be oxidized to cysteine sulphonic acid in the cellular response to H2O2. Loss of DJ-1 function may lead to neurodegeneration.
Protein type: EC 3.4.-.-; Nuclear receptor co-regulator; Transcription regulation; Tumor suppressor
Chromosomal Location of Human Ortholog: 5q36
Cellular Component: axon; cell-cell adherens junction; chromatin; cytoplasm; cytosol; endoplasmic reticulum; membrane raft; mitochondrial intermembrane space; mitochondrial matrix; mitochondrial respiratory chain complex I; mitochondrion; neuron projection; nucleus; perinuclear region of cytoplasm; plasma membrane; PML body
Molecular Function: androgen receptor binding; cadherin binding; copper ion binding; cytokine binding; double-stranded DNA binding; enzyme binding; identical protein binding; kinase binding; mercury ion binding; mRNA binding; oxidoreductase activity, acting on peroxide as acceptor; peptidase activity; peroxiredoxin activity; protein binding; protein homodimerization activity; receptor binding; single-stranded DNA binding; superoxide dismutase copper chaperone activity; transcription coactivator activity; transcription factor binding
Biological Process: adult locomotory behavior; autophagy; detoxification of copper ion; detoxification of mercury ion; DNA repair; dopamine uptake; enzyme active site formation via L-cysteine sulfinic acid; fertilization; glucose homeostasis; glycolate biosynthetic process; hydrogen peroxide metabolic process; inflammatory response; insulin secretion; lactate biosynthetic process; membrane depolarization; membrane hyperpolarization; methylglyoxal metabolic process; mitochondrion organization; negative regulation of apoptosis; negative regulation of neuron apoptosis; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein binding; negative regulation of protein catabolic process; negative regulation of protein export from nucleus; negative regulation of protein kinase activity; negative regulation of protein phosphorylation; negative regulation of protein sumoylation; negative regulation of protein ubiquitination; negative regulation of ubiquitin-protein ligase activity; positive regulation of acute inflammatory response to antigenic stimulus; positive regulation of interleukin-8 production; positive regulation of NAD(P)H oxidase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; protein deglycosylation; protein stabilization; proteolysis; regulation of inflammatory response; regulation of mitochondrial membrane potential; regulation of neuron apoptosis; regulation of TRAIL receptor biosynthetic process; response to drug; response to hydrogen peroxide; response to oxidative stress; single fertilization; synaptic transmission, dopaminergic
Research Articles on PARK7
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Product Notes
The PARK7 park7 (Catalog #AAA2001473) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Parkinson Disease Protein 7 (PARK7) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Parkinson Disease Protein 7 (PARK7) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PARK7 park7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSG SEF-MASKRA LVIL AKGAEEMETV IPVDIMRRAG IKVTVAGLAG KDPVQCSRDV VICPDTSLEE AKTQGPYDVV VLPGGNLGAQ NLSESALVKE ILKEQENRKG LIAAICAGPT ALLAHEVGFG CKVTSHPLAK DKMMNGSHYS YSESRVEKDG LILTSRGPGT SFEFALAIVE ALSGKDMANQ VKAPLVLKD. It is sometimes possible for the material contained within the vial of "Parkinson Disease Protein 7 (PARK7), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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