Rabbit DcR3 (NT) Antibody
Anti-DcR3 (NT) Antibody
Applications
Immunoblot, Western Blot
Synonyms
DcR3 (NT); Anti-DcR3 (NT) Antibody; Anti-DcR3 (NT); anti-DcR3 (NT) antibody
Host
Rabbit
Specificity
Anti-DcR3 (NT) [Rabbit antibody to peptide corresponding to aa 31-46 of human DcR3 precursor. Recognizes human, mouse, and rat DcR3.]
This antibody recognizes human, mouse, and rat DcR3 (33 kD).
This antibody recognizes human, mouse, and rat DcR3 (33 kD).
Form/Format
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
Applicable Applications for anti-DcR3 (NT) antibody
Immunoblot
Application Notes
Immunoblotting: use at 1:500-1:1,000 dilution.
Positive control: Human heart tissue lysate.
Positive control: Human heart tissue lysate.
Antigen
Peptide corresponding to aa 31- 46 of human DcR3 precursor.
Stabilizer
None
Preservatives
0.02% sodium azide.
Dilutions Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
Related Product Information for anti-DcR3 (NT) antibody
Apoptosis is induced by certain cytokines including TNF and Fas ligand through their death domain-containing receptors. Several novel members in the TNF receptor family, including DR3, DR4, DR5 and DR6, function as cell death receptors. Two decoy receptors, DcR1 and DcR2, compete with DR4 and DR5 for binding of their ligand, TRAIL. Another decoy receptor, DcR3/TR6 was discovered recently. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane-associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasLand LIGHT-induced apoptosis. DcR3 transcript is expressed in some lung and colon carcinomas and in some normal tissues.
Product Categories/Family for anti-DcR3 (NT) antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
decoy receptor 3 variant 2
NCBI Description
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
Similar Products
Product Notes
The DcR3 (NT) (Catalog #AAA194061) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's DcR3 (NT) can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Human heart tissue lysate. Researchers should empirically determine the suitability of the DcR3 (NT) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DcR3 (NT), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
