Testing Data
(Detection of ~87kDa ENaC beta in mouse kidney homogenate at 1ug/ml.)
Mouse ENaC beta Monoclonal Antibody | anti-Scnn1b antibody
ENaC beta Monoclonal Antibody
Gene Names
Scnn1b; RNENACB
Applications
Immunoblot, Western Blot
Synonyms
ENaC beta; Monoclonal Antibody; ENaC beta Monoclonal Antibody; anti-Scnn1b antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
160000
Form/Format
Protein G-purified antibody (1mg/ml) in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Sequence Length
638
Applicable Applications for anti-Scnn1b antibody
Immunoblot
Application Notes
Immunoblot: 1ug/ml
Dilute in PBS or medium that is identical to that used in the assay system
Dilute in PBS or medium that is identical to that used in the assay system
Immunogen
Synthetic peptide corresponding to C-terminal aa 617-638 of rat ENaC alpha.
Preparation and Storage
This antibody is stable for at least one (1) year at-20 degree C.
Testing Data
(Detection of ~87kDa ENaC beta in mouse kidney homogenate at 1ug/ml.)
Testing Data
(Detection of ~87kDa ENaC beta in mouse kidney homogenate at 1ug/ml.)
Related Product Information for anti-Scnn1b antibody
The epithelial sodium channel (ENaC) is a membrane-bound ion-channel that is selectively permeable to Na+ ions and that is assembled as a heterotrimer composed of three homologous subunits alpha, beta, and gamma. It is involved primarily in the reabsorption of sodium ions in the collecting ducts of the kidney's nephrons. These channels mediate the first step of active sodium reabsorption essential for the maintenance of body salt and water homeostasis. In vertebrates, the channels control reabsorption of sodium in kidney, colon, lung and sweat glands; they also play a role in taste perception.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
71,995 Da
NCBI Official Full Name
amiloride-sensitive sodium channel subunit beta
NCBI Official Synonym Full Names
sodium channel epithelial 1 beta subunit
NCBI Official Symbol
Scnn1b
NCBI Official Synonym Symbols
RNENACB
NCBI Protein Information
amiloride-sensitive sodium channel subunit beta
UniProt Protein Name
Amiloride-sensitive sodium channel subunit beta
Protein Family
UniProt Gene Name
Scnn1b
UniProt Synonym Gene Names
Beta-ENaC
NCBI Description
acts as an epithelial sodium ion channel; regulates salt and fluid transport in the kidney [RGD, Feb 2006]
Uniprot Description
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Research Articles on Scnn1b
Similar Products
Product Notes
The Scnn1b scnn1b (Catalog #AAA191312) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ENaC beta can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblot: 1ug/ml Dilute in PBS or medium that is identical to that used in the assay system. Researchers should empirically determine the suitability of the Scnn1b scnn1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ENaC beta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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