Testing Data
Rabbit Beclin2 Polyclonal Antibody | anti-BECN2 antibody
Beclin2
Gene Names
BECN2; BECN1L1; BECN1P1
Applications
Immunoblot, Western Blot
Synonyms
Beclin2; Polyclonal Antibody; anti-BECN2 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody recognizes human and rat Beclin 2.
Form/Format
Peptide affinity-purified antibody in PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Concentration
1mg/ml (varies by lot)
Sequence Length
431
Applicable Applications for anti-BECN2 antibody
Immunoblotting (IB)
Application Notes
Immunoblotting: use at 1-2ug/ml. A band of ~50kDa is detected.
Dilute in PBS or medium that is identical to that used in the assay system.
Dilute in PBS or medium that is identical to that used in the assay system.
Antigen
Synthetic peptide corresponding to mid-protein amino acids of human Beclin 2.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-BECN2 antibody
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Beclin 2 is an Atg6/Beclin family member that functions in two distinct lysosomal degradation pathways, autophagy and the downregulation of certain seven- transmembrane-spanning GPCRs. Its role in GPCR lysosomal degradation does not involve Beclin 1 or other Beclin 1/2-interacting proteins such as ATG14 and VPS34 that function in autophagy. Its role in lysosomal degradation also appears to differ from other autophagy- independent functions previously described for yeast Atg6/Vps30 or mammalian Beclin 1, such as vacuolar protein sorting and EGFR degradation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,153 Da
NCBI Official Full Name
beclin-2
NCBI Official Synonym Full Names
beclin 2
NCBI Official Symbol
BECN2
NCBI Official Synonym Symbols
BECN1L1; BECN1P1
NCBI Protein Information
beclin-2
UniProt Protein Name
Beclin-2
Protein Family
UniProt Gene Name
BECN2
Uniprot Description
BECN1L1: May play a role in autophagy and antiviral host defense (Potential). Belongs to the beclin family.
Chromosomal Location of Human Ortholog: 1q43
Molecular Function: protein binding
Biological Process: autophagic vacuole formation; autophagy; cellular response to nitrogen starvation; CVT pathway; endosome to lysosome transport; late endosome to vacuole transport
Research Articles on BECN2
Similar Products
Product Notes
The BECN2 becn2 (Catalog #AAA191011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Beclin2 can be used in a range of immunoassay formats including, but not limited to, Immunoblotting (IB). Immunoblotting: use at 1-2ug/ml. A band of ~50kDa is detected. Dilute in PBS or medium that is identical to that used in the assay system. Researchers should empirically determine the suitability of the BECN2 becn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Beclin2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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