Mouse HTLV-1 Tax Monoclonal Antibody | anti-HTLV-1 Tax antibody
HTLV-1 Tax Monoclonal Antibody
Applications
ELISA, Immunoblot, Western Blot, Immunohistochemistry
Synonyms
HTLV-1 Tax; Monoclonal Antibody; HTLV-1 Tax Monoclonal Antibody; Anti-HTLV-1 Tax; anti-HTLV-1 Tax antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Specificity
This antibody reacts with HTLV-1 Tax expressed in transiently transfected cells.
Form/Format
100ug, Protein A-purified, lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
Applicable Applications for anti-HTLV-1 Tax antibody
ELISA (EIA), Immunoblot (IB), Immunohistochemistry (IHC)
Application Notes
ELISA: Use at 0.1-1.0ug/ml.
Immunoblotting: Use at 2-10ug/ml. A band of ~42kDa is detected
Immunohistochemistry: Use at 2-20ug/ml.
Immunoblotting: Use at 2-10ug/ml. A band of ~42kDa is detected
Immunohistochemistry: Use at 2-20ug/ml.
Antigen
Recombinant full-length HTLV- Tax protein.
Preparation and Storage
This product is stable for at least one (1) year at -20 degree C to -70 degree C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
Related Product Information for anti-HTLV-1 Tax antibody
The nonstructural regulatory Tax proteins are unique characteristics of delta retroviruses, a subgroup of retroviruses, which confers long-term persistent infection to mammalian lymphocytes. These proteins are crucial for productive viral replication, and they stimulate the proliferation of host lymphocytic cells. Tax has been shown to be oncogenic because it transforms and immortalizes rodent fibroblasts and human T-lymphocytes. Tax also stimulates cell growth by direct binding to cyclin-dependent kinase holenzymes and/or inactivating tumor suppressors (e.g. p53, DLG). Moreover, Tax silences cellular checkpoints, which guard against DNA structural damage and chromosomal missegregation, thereby favoring the manifestation of a mutator phenotype in cells.
Product Categories/Family for anti-HTLV-1 Tax antibody
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Product Notes
The HTLV-1 Tax (Catalog #AAA190953) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HTLV-1 Tax can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoblot (IB), Immunohistochemistry (IHC). ELISA: Use at 0.1-1.0ug/ml. Immunoblotting: Use at 2-10ug/ml. A band of ~42kDa is detected Immunohistochemistry: Use at 2-20ug/ml. Researchers should empirically determine the suitability of the HTLV-1 Tax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HTLV-1 Tax, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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