Testing Data
Mouse VGlut2 Monoclonal Antibody | anti-SLC17A6 antibody
VGlut2 Transporter Monoclonal Antibody
Gene Names
SLC17A6; DNPI; VGLUT2
Applications
Immunoblot, Western Blot, Immunohistochemistry
Synonyms
VGlut2; Monoclonal Antibody; VGlut2 Transporter Monoclonal Antibody; Anti-VGlut2 Transporter; anti-SLC17A6 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes human, mouse, and rat VGlut2.
Sequence Length
582
Applicable Applications for anti-SLC17A6 antibody
Immunoblot (IB), Immunohistochemistry (IHC)
Application Notes
Immunoblotting: Use at 1-2ug/ml. A band of ~60kDa is detected.
Immunohistochemistry: Use at 1-5ug/ml.
Immunohistochemistry: Use at 1-5ug/ml.
Antigen
Fusion protein corresponding to aa 501-582 (cytoplasmic C-terminus) of rat VGlut2 (accession no. NP_445879).
Positive Control
Rat brain lysate.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This product is stable for at least 1 year at -20 degree C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-SLC17A6 antibody
The ATP-dependent, chloride-sensitive vesicular glutamate transporters include VGlut1, VGlut2, and VGlut3. VGlut1 and VGlut2 are expressed in brain in a complementary fashion. VGlut1 is expressed in the telencephalic regions whereas VGlut2 is expressed in the lower brainstem and diencephalic regions. VGlut3 is expressed in a small number of neurons in the striatum, hippocampus, cerebral cortex, and raphe nuclei. Pancreatic alpha and beta cells express VGlut1 and VGlut2 in response to glucose concentrations.
Product Categories/Family for anti-SLC17A6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64,392 Da
NCBI Official Full Name
vesicular glutamate transporter 2
NCBI Official Synonym Full Names
solute carrier family 17 member 6
NCBI Official Symbol
SLC17A6
NCBI Official Synonym Symbols
DNPI; VGLUT2
NCBI Protein Information
vesicular glutamate transporter 2
UniProt Protein Name
Vesicular glutamate transporter 2
Protein Family
UniProt Gene Name
SLC17A6
UniProt Synonym Gene Names
DNPI; VGLUT2; VGluT2
UniProt Entry Name
VGLU2_HUMAN
Uniprot Description
SLC17A6: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11p14.3
Cellular Component: cell junction; integral to membrane; neuron projection; synaptic vesicle membrane
Molecular Function: L-glutamate transmembrane transporter activity; symporter activity
Biological Process: ion transport; neurotransmitter transport; sodium ion transport
Research Articles on SLC17A6
Similar Products
Product Notes
The SLC17A6 slc17a6 (Catalog #AAA190899) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's VGlut2 can be used in a range of immunoassay formats including, but not limited to, Immunoblot (IB), Immunohistochemistry (IHC). Immunoblotting: Use at 1-2ug/ml. A band of ~60kDa is detected. Immunohistochemistry: Use at 1-5ug/ml. Researchers should empirically determine the suitability of the SLC17A6 slc17a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VGlut2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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