Mouse anti-Mouse, rat HCN3 Cyclic nucleotide-gated Channel Monoclonal Antibody | anti-HCN3 antibody
Anti-HCN3 Cyclic Nucleotide-Gated Channel Monoclonal Antibody
Reactivity
Mouse, rat
Applications
Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
HCN3 Cyclic nucleotide-gated Channel; Monoclonal Antibody; Anti-HCN3 Cyclic Nucleotide-Gated Channel Monoclonal Antibody; anti-HCN3 antibody
Host
Mouse
Reactivity
Mouse, rat
Clonality
Monoclonal
Isotype
lgG1
Clone Number
S141-28
Specificity
HCN3 Cyclic nucleotide-gated Channel
This antibody recognizes mouse and rat HCN3. It does not cross-react with other HCNs.
This antibody recognizes mouse and rat HCN3. It does not cross-react with other HCNs.
Form/Format
100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.
Sequence Positions
660-779
Applicable Applications for anti-HCN3 antibody
Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence
Application Notes
Immunoblotting: use at 1-10ug/ml. A band of ~90kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate
Antigen
Fusion protein aa 660-779 (cytoplasmic C-terminus) of mouse HCN3 (accession number O88705).
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Related Product Information for anti-HCN3 antibody
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN3, play a crucial role in the regulation of cell excitability. They contribute to spontaneous rhythmic activity in the heart and brain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
hyperpolarization-activated, cyclic nucleotide-gated K+ 3-like
NCBI Official Symbol
HCN3
NCBI Protein Information
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
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Product Notes
The HCN3 (Catalog #AAA190602) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 660-779. The Anti-HCN3 Cyclic Nucleotide-Gated Channel Monoclonal Antibody reacts with Mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's HCN3 Cyclic nucleotide-gated Channel can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence. Immunoblotting: use at 1-10ug/ml. A band of ~90kDa is detected. Immunohistochemistry and Immunocytochemistry. use at 0.1-1ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate. Researchers should empirically determine the suitability of the HCN3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCN3 Cyclic nucleotide-gated Channel, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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