Mouse HCN1 Cyclic nucleotide-gated Channel Monoclonal Antibody | anti-hcn1 antibody
Anti-HCN1 Cyclic Nucleotide-Gated Channel Monoclonal Antibody
Reactivity
Human, mouse, rat
Applications
Immunoblot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
HCN1 Cyclic nucleotide-gated Channel; Monoclonal Antibody; Anti-HCN1 Cyclic Nucleotide-Gated Channel Monoclonal Antibody; anti-hcn1 antibody
Host
Mouse
Reactivity
Human, mouse, rat
Clonality
Monoclonal
Isotype
lgG1
Clone Number
S70-28
Specificity
HCN1 Cyclic nucleotide-gated Channel
This antibody recognizes human, mouse, and rat HCN1. It does not cross-react with HCN2.
This antibody recognizes human, mouse, and rat HCN1. It does not cross-react with HCN2.
Form/Format
100ug in PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography
Sequence Positions
778-910
Applicable Applications for anti-hcn1 antibody
Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence
Application Notes
Immunoblotting: use at 1-10ug/ml. A band of ~100kDa is detected. Immunohistochemistry and Immunocytochemistry: use at 0.1-1 ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate
Antigen
Fusion protein aa 778-910 (C-terminus) of rat HCN! (accession number Q9JKBO).
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Related Product Information for anti-hcn1 antibody
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulation of cell excitability. They contribute to spontaneous rhythmic activity in the heart and brain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
hyperpolarization-activated cyclic nucleotide-gated cation channel 1
NCBI Official Symbol
hcn1
NCBI Protein Information
hyperpolarization-activated cyclic nucleotide-gated cation channel 1
Protein Family
Similar Products
Product Notes
The hcn1 (Catalog #AAA190535) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 778-910. The Anti-HCN1 Cyclic Nucleotide-Gated Channel Monoclonal Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's HCN1 Cyclic nucleotide-gated Channel can be used in a range of immunoassay formats including, but not limited to, Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence. Immunoblotting: use at 1-10ug/ml. A band of ~100kDa is detected. Immunohistochemistry and Immunocytochemistry: use at 0.1-1 ug/ml. Immunofluorescence: use at 1-10ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Rat brain lysate. Researchers should empirically determine the suitability of the hcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HCN1 Cyclic nucleotide-gated Channel, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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