Western Blot (WB)
(Anti- ADIPOR1 Picoband antibody, MBS177989, Western blottingAll lanes: Anti ADIPOR1 (MBS177989) at 0.5ug/mlLane 1: Rat Thymus Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugLane 4: A549 Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 43KD )
anti-Human, Rat ADIPOR1 Polyclonal Antibody | anti-ADIPOR1 antibody
Anti-ADIPOR1 Antibody
Western Blot (WB)
(Anti- ADIPOR1 Picoband antibody, MBS177989, Western blottingAll lanes: Anti ADIPOR1 (MBS177989) at 0.5ug/mlLane 1: Rat Thymus Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugLane 4: A549 Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 43KD )
Western Blot (WB)
(Anti- ADIPOR1 Picoband antibody, MBS177989, Western blottingAll lanes: Anti ADIPOR1 (MBS177989) at 0.5ug/mlLane 1: Rat Thymus Tissue Lysate at 50ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugLane 4: A549 Whole Cell Lysate at 40ugPredicted bind size: 43KDObserved bind size: 43KD )
Background: ADIPOR1 is known as Adiponectin receptor protein 1. This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
Uniprot Description
ADIPOR1: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. Belongs to the ADIPOR family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: integral to membrane; intrinsic to plasma membrane; membrane; plasma membrane
Molecular Function: adiponectin binding; identical protein binding; metal ion binding; protein heterodimerization activity; protein kinase binding
Biological Process: adiponectin-mediated signaling pathway; fatty acid oxidation; G-protein coupled receptor protein signaling pathway; glucose homeostasis; hormone-mediated signaling; leptin-mediated signaling pathway; negative regulation of cell growth; positive regulation of insulin receptor signaling pathway; positive regulation of JAK-STAT cascade; regulation of lipid metabolic process
Research Articles on ADIPOR1
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Product Notes
The ADIPOR1 adipor1 (Catalog #AAA177989) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-ADIPOR1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADIPOR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the ADIPOR1 adipor1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADIPOR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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