Western Blot (WB)
(Anti- LAMP1antibody, MBS176049, Western blottingAll lanes: Anti LAMP1 (MBS176049) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugPredicted bind size: 45KDObserved bind size: 80KD )
Rabbit LAMP1 Polyclonal Antibody | anti-LAMP1 antibody
Anti-LAMP1 antibody
Gene Names
LAMP1; LAMPA; CD107a; LGP120
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
LAMP1; Polyclonal Antibody; Anti-LAMP1 antibody; Lysosome-associated membrane glycoprotein 1(LAMP-1); lysosomal-associated membrane protein 1; CD107 antigen like family member A antibody; CD107 antigen-like family member A antibody; CD107a antibody; CD107a antigen antibody; LAMP 1 antibody; LAMP-1 antibody; LAMP1 antibody; LAMP1_HUMAN antibody; LAMPA antibody; LGP120 antibody; lgpA antibody; Lysosomal membrane glycoprotein 120KD antibody; Lysosomal Associated Membrane Protein 1 antibody; Lysosome associated membrane glycoprotein 1 antibody; Lysosome-associated membrane glycoprotein 1 antibody; Lysosome-associated membrane protein 1 antibody; OTTHUMP00000040663 antibody; anti-LAMP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
417
Applicable Applications for anti-LAMP1 antibody
Western Blot (WB)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human LAMP1 (403-417aa YLVGRKRSHAGYQTI), different from the related mouse and rat sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti- LAMP1antibody, MBS176049, Western blottingAll lanes: Anti LAMP1 (MBS176049) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugPredicted bind size: 45KDObserved bind size: 80KD )
Western Blot (WB)
(Anti- LAMP1antibody, MBS176049, Western blottingAll lanes: Anti LAMP1 (MBS176049) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: A549 Whole Cell Lysate at 40ugPredicted bind size: 45KDObserved bind size: 80KD )
Related Product Information for anti-LAMP1 antibody
Description: Rabbit IgG polyclonal antibody for Lysosome-associated membrane glycoprotein 1(LAMP1) detection. Tested with WB in Human, Mouse, Rat.
Background: LAMP1(lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used.
Background: LAMP1(lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
38,986 Da
NCBI Official Full Name
Lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
NCBI Protein Information
lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
Protein Family
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1; Lysosome-associated membrane protein 1
UniProt Entry Name
LAMP1_HUMAN
NCBI Description
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
Uniprot Description
LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 13q34
Cellular Component: lysosome; integral to plasma membrane; dendrite; multivesicular body; cell soma; membrane; cytoplasm; late endosome; melanosome; plasma membrane; endosome membrane; sarcolemma; external side of plasma membrane
Molecular Function: protein domain specific binding; protein binding; enzyme binding
Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; viral reproduction; protein stabilization; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity
Research Articles on LAMP1
Similar Products
Product Notes
The LAMP1 lamp1 (Catalog #AAA176049) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LAMP1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the LAMP1 lamp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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