Myosin Light Chain Protein
Myosin Light Chain (MLC), Human Heart
Purity
>= 95% (SDS-PAGE)
Synonyms
Myosin Light Chain; Myosin Light Chain (MLC); Human Heart; MLC; MYLK3; Myosin Light-Chain Kinase; Human Heart - >=95% (SDS-PAGE); Myosin Light Chain protein
Purity/Purification
>= 95% (SDS-PAGE)
Form/Format
Lyophilized
Source
Human Heart
EC Number
2.7.11.18
Reconstitution
Neutral pH buffer of choice. Avoid extreme high and low pH
Recertification
5 years
Protein
1 mg protein/mg solid (A280 E=0.211)
Preparation and Storage
At -20 degree C
Related Product Information for Myosin Light Chain protein
MyBioSource sells human heart Myosin Light Chain (MLC) for research, life science and manufacturing uses.
Custom preparations, technical support, bulk quantities and aliquoting available.
These enzymes are important in the mechanism of contraction in muscle. Once there is an influx of calcium cations (Ca++) into the muscle, either from the sarcoplasmic reticulum or, more importantly, from the extracellular space, contraction of smooth muscle fibers may begin. First, the calcium will bind to calmodulin. This binding will activate MLCK, which will go on to phosphorylate the myosin light chain at serine residue 19. This will enable the myosin crossbridge to bind to the actin filament and allow contraction to begin (through the crossbridge cycle). Since smooth muscle does not contain a troponin complex like striated muscle does, this mechanism is the main pathway for regulating smooth muscle contraction
Custom preparations, technical support, bulk quantities and aliquoting available.
These enzymes are important in the mechanism of contraction in muscle. Once there is an influx of calcium cations (Ca++) into the muscle, either from the sarcoplasmic reticulum or, more importantly, from the extracellular space, contraction of smooth muscle fibers may begin. First, the calcium will bind to calmodulin. This binding will activate MLCK, which will go on to phosphorylate the myosin light chain at serine residue 19. This will enable the myosin crossbridge to bind to the actin filament and allow contraction to begin (through the crossbridge cycle). Since smooth muscle does not contain a troponin complex like striated muscle does, this mechanism is the main pathway for regulating smooth muscle contraction
Product Categories/Family for Myosin Light Chain protein
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Product Notes
The Myosin Light Chain (Catalog #AAA173247) is a Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Myosin Light Chain, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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