Lipase Active Protein | PNLIP active protein
Lipase, Human Pancreas
Appearance: Tan powder
Handling: Handle as a potentially hazardous substance.
Storage Note: Protect from moisture
Shipping Note: Cold pack
Custom preparations, technical support, bulk quantities and aliquoting available.
Human Pancreatic lipase enzyme is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in water-insoluble, lipid substrates. Most lipases act at a specific position on the glycerol backbone of a lipid substrate (A1, A2 or A3).
Human pancreatic lipase clinical significance: Investigations of pancreatic disorders, pancreatitis, acute and chronic renal disease.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Uniprot Description
PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
Protein type: EC 3.1.1.3; Secreted, signal peptide; Secreted; Lipid Metabolism - glycerolipid; Hydrolase
Chromosomal Location of Human Ortholog: 10q26.1
Cellular Component: extracellular region
Molecular Function: triacylglycerol lipase activity; metal ion binding
Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process
Disease: Pancreatic Lipase Deficiency
Research Articles on PNLIP
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Product Notes
The PNLIP lipf (Catalog #AAA173153) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Lipase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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