Sheep Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit | RXFP1 elisa kit

Sheep Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit

Cat. Num. AAA16954

• Gene Names: RXFP2; LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
• Reactivity: Sheep
• Synonyms: Relaxin/Insulin Like Family Peptide Receptor 1; Sheep Relaxin/Insulin Like Family Peptide Receptor 1 ELISA Kit; RXFP1 elisa kit

• Reactivity: Sheep
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.
• Sequence Length: 754

• Assay Type: Quantitative Sandwich
• Detection Range: 0.25ng/ml-8ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for RXFP1 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of RXFP1 (hereafter termed "analyte") in undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 18677729
• NCBI GeneID: 122042
• NCBI Accession #: NP_570718.1
• NCBI GenBank Nucleotide #: NM_130806.3
• UniProt Accession #: Q8WXD0; Q3KU23; B1ALE9
• Molecular Weight: 86,453 Da
• NCBI Official Full Name: relaxin receptor 2 isoform 1
• NCBI Official Synonym Full Names: relaxin/insulin-like family peptide receptor 2
• NCBI Official Symbol: RXFP2
• NCBI Official Synonym Symbols: LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2
• NCBI Protein Information: relaxin receptor 2; G-protein coupled receptor 106; relaxin family peptide receptor 2; G protein coupled receptor affecting testicular descent; G-protein coupled receptor affecting testicular descent; leucine-rich repeat-containing G protein-coupled receptor 8; leucine-rich repeat-containing G-protein coupled receptor 8
• UniProt Protein Name: Relaxin receptor 2
• Protein Family: Relaxin receptor
• UniProt Gene Name: RXFP2
• UniProt Synonym Gene Names: GPR106; GREAT; LGR8
• UniProt Entry Name: RXFP2_HUMAN

NCBI Description

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Uniprot Description

LGR8: the relaxin receptor is a G-protein coupled receptor (GPCR) that leads to the stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 13q13.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: peptide hormone binding; protein-hormone receptor activity

Biological Process: negative regulation of cell proliferation; positive regulation of cAMP biosynthetic process; male gonad development; G-protein signaling, adenylate cyclase inhibiting pathway; oocyte maturation; G-protein signaling, adenylate cyclase activating pathway; negative regulation of apoptosis

Disease: Cryptorchidism, Unilateral Or Bilateral