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COVID 19 NSP3 Coronavirus Recombinant Protein | COVID-19 recombinant protein
Recombinant SARS-CoV-2 (2019-nCoV) NSP3
Applications
Immunogen
Purity
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
Synonyms
COVID 19 NSP3 Coronavirus; Recombinant SARS-CoV-2 (2019-nCoV) NSP3; 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; NSP3; COVID-19 recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
Form/Format
Lyophilized. Lyophilized from PBS pH 7.4, 5% Trehalose, 5% Mannose?1mM EDTA
Sequence Length
7096
Applicable Applications for COVID-19 recombinant protein
Immunogen
Species
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-1.0mg/mL. Do not vortex.
Preparation and Storage
Store at 2 to 8 degree C for one week.
Store at -20 to -80 degree C for twelve months from the date of receipt.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Shipping: Ice packs
Store at -20 to -80 degree C for twelve months from the date of receipt.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Shipping: Ice packs
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Related Product Information for COVID-19 recombinant protein
Recombinant SARS-CoV-2 NSP3 is produced by E.coli expression system and the target gene encoding Glu1024-Gln1198 is expressed with N-His Tag
Background: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
Background: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
Predicted Molecular Mass: 22.03kDa
Actual Molecular Mass: 25kDa, reducing conditions
Actual Molecular Mass: 25kDa, reducing conditions
NCBI Official Full Name
orf1ab polyprotein
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Product Notes
The COVID-19 (Catalog #AAA156003) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's COVID 19 NSP3 Coronavirus can be used in a range of immunoassay formats including, but not limited to, Immunogen. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 NSP3 Coronavirus, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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