SAMSN Blocking Peptide | SAMSN1 blocking peptide

SAMSN Peptide

Cat. Num. AAA153763

• Gene Names: SAMSN1; SLy2; HACS1; NASH1; SASH2; SH3D6B
• Applications: Blocking (BL)
• Synonyms: SAMSN; SAMSN Peptide; SLy2; HACS1; NASH1; SASH2; SH3D6B; SAM domain-containing protein SAMSN-1; Hematopoietic adaptor containing SH3 and SAM domains 1; SAM domain; SH3 domain and nuclear localization signals 1; SAMSN1 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 373

• Applicable Applications for SAMSN1 blocking peptide: Blocking (BL)
• Application Notes: SAMSN Peptide is used for blocking the activity of SAMSN antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 18 amino acids near the carboxy terminus of human SAMSN.
• Preparation and Storage: Store SAMSN peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 48762709
• NCBI GeneID: 64092
• NCBI Accession #: NP_071419
• NCBI GenBank Nucleotide #: NM_022136.4
• UniProt Accession #: Q9NSI8; Q8NFF7; Q9C041; B3KWJ3; F8WAA1
• Molecular Weight: 49,627 Da
• NCBI Official Full Name: SAM domain-containing protein SAMSN-1 isoform 1
• NCBI Official Synonym Full Names: SAM domain, SH3 domain and nuclear localization signals 1
• NCBI Official Symbol: SAMSN1
• NCBI Official Synonym Symbols: SLy2; HACS1; NASH1; SASH2; SH3D6B
• NCBI Protein Information: SAM domain-containing protein SAMSN-1; SH3-SAM adaptor protein; SAM and SH3 domain containing 2; hematopoietic adaptor containing SH3 and SAM domains 1; SAM domain, SH3 domain and nuclear localisation signals, 1; nuclear localization signals, SAM and SH3 domain containing 1; SAM domain, SH3 domain and nuclear localization signals protein 1; hematopoietic adapter-containing SH3 and sterile alpha-motif (SAM) domains 1; hematopoietic adapter-containing SH3 and sterile α-motif (SAM) domains 1; Src homology domain 3 (SH3)-containing adapter protein SH3 lymphocyte protein 2
• UniProt Protein Name: SAM domain-containing protein SAMSN-1
• Protein Family: SAM domain-containing protein
• UniProt Gene Name: SAMSN1
• UniProt Synonym Gene Names: HACS1
• UniProt Entry Name: SAMN1_HUMAN

NCBI Description

SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008]

Uniprot Description

SAMSN1: an adaptor and scaffold protein containing an SH3 and a SAM (sterile alpha motif) domain. Its expression is induced by B cell activation signals. Two alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 21q11

Cellular Component: ruffle; nucleus; cytosol

Molecular Function: phosphotyrosine binding

Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of adaptive immune response; negative regulation of B cell activation