SLC35D1 blocking peptide
Slc35D1 Peptide
NCBI and Uniprot Product Information
NCBI Description
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Uniprot Description
SLC35D1: Transports both UDP-glucuronic acid (UDP-GlcA) and UDP- N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis. Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD). Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia. Belongs to the TPT transporter family. SLC35D subfamily.
Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: UDP-glucuronic acid transmembrane transporter activity
Biological Process: UDP-glucuronic acid transport; chondroitin sulfate biosynthetic process; embryonic skeletal development; xenobiotic metabolic process; carbohydrate transport; UDP-glucuronate biosynthetic process; transmembrane transport
Disease: Schneckenbecken Dysplasia
Research Articles on SLC35D1
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Product Notes
The SLC35D1 slc35d1 (Catalog #AAA153268) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Slc35D1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Slc35D1 peptide is used for blocking the activity of Slc35D1 antibody. Researchers should empirically determine the suitability of the SLC35D1 slc35d1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Slc35D1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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