ATAD3B blocking peptide

ATAD3B Peptide

Cat. Num. AAA152817

• Gene Names: ATAD3B; TOB3; AAA-TOB3
• Applications: Blocking (BL)
• Synonyms: ATAD3B; ATAD3B Peptide; TOB3; AAA-TOB3; KIAA1273; ATPase family AAA domain-containing protein 3B; ATPase family; AAA domain containing 3B; ATAD3B blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 648

• Applicable Applications for ATAD3B blocking peptide: Blocking (BL)
• Application Notes: ATAD3B peptide is used for blocking the activity of ATAD3B antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 14 amino acids near the carboxy terminus of human ATAD3B.
• Preparation and Storage: Store ATAD3B peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 75677353
• NCBI GeneID: 83858
• NCBI Accession #: NP_114127
• NCBI GenBank Nucleotide #: NM_031921.4
• UniProt Accession #: Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7; A8K3H1
• Molecular Weight: 67,608 Da
• NCBI Official Full Name: ATPase family AAA domain-containing protein 3B
• NCBI Official Synonym Full Names: ATPase family, AAA domain containing 3B
• NCBI Official Symbol: ATAD3B
• NCBI Official Synonym Symbols: TOB3; AAA-TOB3
• NCBI Protein Information: ATPase family AAA domain-containing protein 3B; AAA-ATPase TOB3
• UniProt Protein Name: ATPase family AAA domain-containing protein 3B
• Protein Family: ATPase family AAA domain-containing protein
• UniProt Gene Name: ATAD3B
• UniProt Synonym Gene Names: KIAA1273; TOB3
• UniProt Entry Name: ATD3B_HUMAN

NCBI Description

ATAD3A (MIM 612316) and ATAD3B are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al., 2007 [PubMed 17210950]).[supplied by OMIM, Sep 2008]

Uniprot Description

ATAD3B: May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes. Belongs to the AAA ATPase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: mitochondrial inner membrane

Molecular Function: ATP binding