SAPAP4 Blocking Peptide | DLGAP4 blocking peptide

SAPAP4 Peptide

Cat. Num. AAA152153

• Gene Names: DLGAP4; DAP4; DLP4; DAP-4; SAPAP4; SAPAP-4
• Applications: Blocking (BL)
• Synonyms: SAPAP4; SAPAP4 Peptide; DAP4; DLP4; KIAA0964; Disks large-associated protein 4; DAP-4; discs; large (Drosophila) homolog-associated protein 4; DLGAP4 blocking peptide

• Form/Format: Liquid
• Concentration: 200 ug/mL (varies by lot)
• Sequence Length: 989

• Applicable Applications for DLGAP4 blocking peptide: Blocking (BL)
• Application Notes: SAPAP4 peptide is used for blocking the activity of SAPAP4 antibody.
• Species: Human
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
• Location: 13 amino acids near the center of human SAPAP4.
• Preparation and Storage: Store SAPAP4 peptide at -20 degree C, stable for one year.

NCBI and Uniprot Product Information

• NCBI GI #: 34335253
• NCBI GeneID: 22839
• NCBI Accession #: NP_055717
• NCBI GenBank Nucleotide #: NM_014902.5
• UniProt Accession #: Q9Y2H0; Q5QPG4; Q5T2Y4; Q5T2Y5; Q9H137; Q9H138; Q9H1L7; E1P5T5
• Molecular Weight: 49,478 Da
• NCBI Official Full Name: disks large-associated protein 4 isoform a
• NCBI Official Synonym Full Names: discs, large (Drosophila) homolog-associated protein 4
• NCBI Official Symbol: DLGAP4
• NCBI Official Synonym Symbols: DAP4; DLP4; DAP-4; SAPAP4; SAPAP-4
• NCBI Protein Information: disks large-associated protein 4; PSD-95/SAP90-binding protein 4; SAP90/PSD-95-associated protein 4
• UniProt Protein Name: Disks large-associated protein 4
• Protein Family: Disks large-associated protein
• UniProt Gene Name: DLGAP4
• UniProt Synonym Gene Names: DAP4; KIAA0964; SAPAP4; DAP-4; SAPAP-4
• UniProt Entry Name: DLGP4_HUMAN

NCBI Description

The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SAPAP4: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Membrane protein, peripheral

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: membrane; synapse

Molecular Function: protein binding

Biological Process: cell-cell signaling