Immunohistochemistry (IHC)
(Immunohistochemistry of VARP in human small intestine with VARP antibody at 5 μg/mL.)
Rabbit anti-Human VARP Polyclonal Antibody | anti-ANKRD27 antibody
VARP Antibody
Gene Names
ANKRD27; VARP; PP12899
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
VARP Antibody is affinity chromatography purified via peptide column.
Synonyms
VARP; Polyclonal Antibody; VARP Antibody; PP12899; Ankyrin repeat domain-containing protein 27; VPS9 domain-containing protein; ankyrin repeat domain 27 (VPS9 domain); anti-ANKRD27 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
VARP Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1050
Applicable Applications for anti-ANKRD27 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 mug/mL.
Conjugate
Unconjugated
Immunogen
VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP.
Buffer
VARP Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
VARP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Immunohistochemistry (IHC)
(Immunohistochemistry of VARP in human small intestine with VARP antibody at 5 μg/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of VARP in human small intestine with VARP antibody at 5 μg/mL.)
Related Product Information for anti-ANKRD27 antibody
VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116,984 Da
NCBI Official Full Name
ankyrin repeat domain-containing protein 27
NCBI Official Synonym Full Names
ankyrin repeat domain 27 (VPS9 domain)
NCBI Official Symbol
ANKRD27
NCBI Official Synonym Symbols
VARP; PP12899
NCBI Protein Information
ankyrin repeat domain-containing protein 27; VPS9-ankyrin-repeat protein; VPS9 domain-containing protein; Vps9 domain and ankyrin-repeat-containing protein
UniProt Protein Name
Ankyrin repeat domain-containing protein 27
Protein Family
UniProt Gene Name
ANKRD27
UniProt Entry Name
ANR27_HUMAN
Uniprot Description
ANKRD27: May be a Rab21 guanine exchange factor and regulate endosome dynamics.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 19q13.11
Cellular Component: cytoplasmic vesicle membrane; membrane; lysosome; early endosome; late endosome; cytoplasm; melanosome; plasma membrane
Molecular Function: protein binding; guanyl-nucleotide exchange factor activity; GTPase activator activity; Rab GTPase binding
Biological Process: protein transport; early endosome to late endosome transport; positive regulation of GTPase activity
Research Articles on ANKRD27
Similar Products
Product Notes
The ANKRD27 ankrd27 (Catalog #AAA151499) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VARP Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VARP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 mug/mL. Researchers should empirically determine the suitability of the ANKRD27 ankrd27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VARP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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