Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS1497106 at dilution of 1:100)
Rabbit anti-Human ATXN7L3 Polyclonal Antibody | anti-ATXN7L3 antibody
ATXN7L3 Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS1497106 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS1497106 at dilution of 1:100)
NCBI and Uniprot Product Information
Uniprot Description
ataxin-7L3: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Belongs to the SGF11 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q21.31
Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity; protein binding; transcription coactivator activity; zinc ion binding
Biological Process: establishment and/or maintenance of chromatin architecture; histone deubiquitination; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on ATXN7L3
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Product Notes
The ATXN7L3 atxn7l3 (Catalog #AAA1497106) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ATXN7L3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATXN7L3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC:1:20-1:200. Researchers should empirically determine the suitability of the ATXN7L3 atxn7l3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATXN7L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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