Rabbit anti-Human PSG3 Polyclonal Antibody | anti-PSG3 antibody

PSG3 Antibody

Cat. Num. AAA1496619

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >95%, Protein G Purified
• Synonyms: PSG3; Polyclonal Antibody; PSG3 Antibody; Pregnancy-specific beta-1-glycoprotein 3; PS-beta-G-3; PSBG-3; Pregnancy-specific glycoprotein 3; Carcinoembryonic antigen SG5; anti-PSG3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G Purified
• Sequence Length: 428

• Applicable Applications for anti-PSG3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: WB:1:500-2000; IHC:1:20-1:200
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugate: Non-conjugated
• Immunogen: Recombinant human Pregnancy-specific beta-1-glycoprotein 3 protein
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: PSG3 antibody at 10ug/mlLane 1: MCF7 whole cell lysateLane 2: Hela whole cell lysateLane 3: HepG-2 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 48 kDaObserved band size: 48 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1496619 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS1496619 at dilution of 1:100)

Related Product Information for anti-PSG3 antibody

defense response, female pregnancy

NCBI and Uniprot Product Information

• NCBI GI #: 109240546
• NCBI GeneID: 5671
• NCBI Accession #: NP_066296.2
• NCBI GenBank Nucleotide #: NM_021016.3
• UniProt Accession #: Q16557; Q08265; Q9BRW2; Q9UPL4; Q9UQ77
• Molecular Weight: 47,945 Da
• NCBI Official Full Name: pregnancy-specific beta-1-glycoprotein 3
• NCBI Official Synonym Full Names: pregnancy specific beta-1-glycoprotein 3
• NCBI Official Symbol: PSG3
• NCBI Protein Information: pregnancy-specific beta-1-glycoprotein 3
• UniProt Protein Name: Pregnancy-specific beta-1-glycoprotein 3
• Protein Family: Pregnancy-specific beta-1-glycoprotein
• UniProt Gene Name: PSG3
• UniProt Synonym Gene Names: PS-beta-G-3; PSBG-3; Pregnancy-specific glycoprotein 3
• UniProt Entry Name: PSG3_HUMAN

NCBI Description

The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]

Uniprot Description

PSG3: Belongs to the immunoglobulin superfamily. CEA family

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular region

Biological Process: defense response; female pregnancy