Rabbit anti-Human ATP-dependent RNA helicase DDX39A Polyclonal Antibody | anti-DDX39A antibody
Rabbit anti-human ATP-dependent RNA helicase DDX39A polyclonal Antibody(DDX39A)
IHC:1:20-1:200
Western Blot (WB)
(All lanes: ATP-dependent RNA helicase DDX39A antibody at 2ug/mlLane 1:A431 whole cell lysateLane 2:293T whole cell lysateLane 3:HepG2 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 50,37,31 kDaObserved band size: 49 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human skin tissue using MBS1496058 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human testis using MBS1496058 at dilution 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
Uniprot Description
DDX39: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. Belongs to the DEAD box helicase family. DECD subfamily.
Protein type: RNA-binding; RNA splicing; Helicase; EC 3.6.4.13
Chromosomal Location of Human Ortholog: 19p13.12
Cellular Component: cytoplasm; membrane; nucleus; spliceosome
Molecular Function: ATP binding; ATP-dependent RNA helicase activity; protein binding
Biological Process: mRNA export from nucleus; nuclear mRNA splicing, via spliceosome; regulation of gene expression; response to DNA damage stimulus; RNA secondary structure unwinding
Research Articles on DDX39A
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Product Notes
The DDX39A ddx39a (Catalog #AAA1496058) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human ATP-dependent RNA helicase DDX39A polyclonal Antibody(DDX39A) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ATP-dependent RNA helicase DDX39A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the DDX39A ddx39a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ATP-dependent RNA helicase DDX39A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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