Uncharacterized GTP-binding protein At5g64813 (At5g64813) Recombinant Protein | At5g64813 recombinant protein

Recombinant Arabidopsis thaliana Uncharacterized GTP-binding protein At5g64813 (At5g64813)

Cat. Num. AAA1469833

• Gene Names: LIP1; Light Insensitive Period1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Uncharacterized GTP-binding protein At5g64813 (At5g64813); Recombinant Arabidopsis thaliana Uncharacterized GTP-binding protein At5g64813 (At5g64813); At5g64813 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-342, Full length protein
• Sequence: MKFWRERERENKEQILAPLCGQVRVLVVGDSGVGKTSLVHLINKGSSIVRPPQTIGCTVGVKHITYGSPASSSSSIQGDSERDFFVELWDVSGHERYKDCRSLFYSQINGVIFVHDLSQRRTKTSLQKWASEVAATGTFSAPLPSGGPGGLPVPYIVVGNKADIAAKEGTKGSSGNLVDAARHWVEKQGLLPSSSEDLPLFESFPGNGGLIAAAKETRYDKEALNKFFRMLIRRRYFSDELPAASPWSISPVPTSSSQRLDEITSDDDQFYKRTSFHGDPYKYNNTIPPLPAQRNLTPPPTLYPQQPVSTPDNYTIPRYSLSSVQETTNNGSARSKRMDINV
• Sequence Length: 342

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 1063743251
• NCBI GeneID: 836603
• NCBI Accession #: NP_001318878.1
• NCBI GenBank Nucleotide #: NM_001345650.1
• UniProt Accession #: Q9C5J9; Q9LV96
• Molecular Weight: 37,741 Da
• NCBI Official Full Name: Ras-related small GTP-binding family protein
• NCBI Official Symbol: LIP1
• NCBI Official Synonym Symbols: Light Insensitive Period1
• NCBI Protein Information: Ras-related small GTP-binding family protein
• UniProt Protein Name: Small GTPase LIP1
• UniProt Gene Name: LIP1

NCBI Description

The LIP1 gene encodes a small GTPase that influences the light input pathway of the plant circadian network. An MBP:LIP1 fusion protein has GTP hydrolyzing abilities in vitro. In plants, LIP1 seems to play a negative role in regulating circadian period that can be suppressed by light. LIP1 also seems to negatively affect light-pulse-dependent resetting of the clock, especially during the first portion of the subjective evening. LIP1 expression levels are not significantly affected by the circadian clock in seedlings grown under LL conditions. The levels of the YFP:LIP1 protein expressed under the control of the 35S promoter, shows a low amplitude variation, with protein levels peaking near the beginning of subjective night under LL conditions. In hypocotyl epidermal cells of dark and light-grown seedlings, a YFP:LIP1 fusion protein can be seen in the cytoplasm and the nucleus, and does not cluster in nuclear speckles. LIP1 may also be involved in photomorphogenesis.

Uniprot Description

Functional small GTPase that acts as a negative factor controlling the light-dependent period shortening of circadian rhythms and light-induced phase resetting during the subjective night (PubMed:17683937). May protect the clock from excessive or mistimed light (PubMed:17683937). Suppresses red and blue light-mediated photomorphogenesis and is required for light-controlled inhibition of endoreplication and tolerance to salt stress (PubMed:23144185). The entrainment of the circadian clock is independent from the other pleiotropic effects (PubMed:23144185). Could be a regulator of seedling establishment (PubMed:23144185).