Serine/threonine-protein kinase Aurora-1 (AUR1) Recombinant Protein | AUR1 recombinant protein
Recombinant Arabidopsis thaliana Serine/threonine-protein kinase Aurora-1 (AUR1)
NCBI and Uniprot Product Information
NCBI Description
Encodes a member of a family of Ser/Thr kinases whose activities peak during cell division. Transcripts are abundant in tissues rich in dividing cells like roots and flowers but are low or absent in fully expanded leaves and stems. In interphase cells, the protein is predominantly nuclear. During mitosis, the protein associates with plant-specific cytoskeletal structures (preprophase band, phragmoplast, nascent cell plate) that are necessary for cytokinesis as well as with the microtubule spindle. It specifically phosphorylates Ser10 of histone H3 and colocalizes with phosphorylated histone H3 during mitosis.
Uniprot Description
Phosphorylates specifically 'Ser-10' of histone H3 in vitro and colocalizes with phosphorylated histone H3 during mitosis. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle. Colocalizes also with gamma-tubulin and function in microtubule organizing centers (MTOCs). In contrast with the mammalian B-type Aurora, AUR1 has no kinase activity toward 'Ser-28' of histone H3.
Research Articles on AUR1
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Product Notes
The AUR1 aur1 (Catalog #AAA1469085) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-294aa; Full Length. The amino acid sequence is listed below: MAIPTETQHQ EKEASDASAA AAQKRWTLSD FDIGKPLGRG KFGHVYLARE KRSNHVVALK VLFKSQLQQS QVEHQLRREV EIQSHLRHPN ILRLYGYFYD QKRVYLILEY AARGELYKDL QKCKYFSERR AATYVASLAR ALIYCHGKHV IHRDIKPENL LIGAQGELKI ADFGWSVHTF NRRRTMCGTL DYLPPEMVES VEHDASVDIW SLGILCYEFL YGVPPFEAME HSDTYRRIVQ VDLKFPPKPI ISASAKDLIS QMLVKESSQR LPLHKLLEHP WIVQNADPSG IYRV. It is sometimes possible for the material contained within the vial of "Serine/threonine-protein kinase Aurora-1 (AUR1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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