Mouse anti-Human Ubiquitin Aldehyde Binding 1 Monoclonal Antibody | anti-OTUB1 antibody
Mouse Anti Human Ubiquitin Aldehyde Binding 1
Reactivity
Human
Applications
ELISA, Western Blot, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Synonyms
Ubiquitin Aldehyde Binding 1; Monoclonal Antibody; Mouse Anti Human Ubiquitin Aldehyde Binding 1; OTUB1 Antibody; Ubiquitin thioesterase OTUB1; Otubain-1; OTU domain-containing ubiquitin aldehyde-binding protein 1; Ubiquitin-specific-processing protease OTUB1; Deubiquitinating enzyme OTUB1; OTUB1; OTB1; OTU1; HSPC263; MGC4584; FLJ20113; FLJ40710; MGC111158; Mouse Anti Human; anti-OTUB1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 heavy chain and k light chain.
Clone Number
PAT17E10AT
Purity/Purification
Antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Form/Format
Sterile filtered colorless solution.
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.
Sequence Length
276
Applicable Applications for anti-OTUB1 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Immunogen
Anti-human OTUB1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human OTUB1 protein 1-271 amino acids purified from E Coli.
Preparation and Storage
12 months at -20 degree C. 1 month at 4 degree C.
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
Related Product Information for anti-OTUB1 antibody
Otubain 1 (OTUB1) belongs to the ovarian tumor (OUT) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system through its interaction with a ubiquitin protease and E3 ubiquitin ligase. OTUB1 is a highly specific ubiquitin iso-peptidase, it cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. OTUB1 is believed to work in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. OTUB1 is a hydrolase that removes conjugated ubiquitin from proteins in vitro and may therefore have a significant regulatory role in the level of protein turnover by preventing degradation. Additionally, OTUB1 is a regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered impassive to antigen re-challenge and no longer respond to their cognate antigen. OTUB1 acts via its interaction with RNF128/GRAIL, which is an essential inductor of CD4 T-cell anergy.
Product Categories/Family for anti-OTUB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
32,082 Da
NCBI Official Full Name
OTUB1, partial
UniProt Protein Name
OTUB1
Protein Family
UniProt Gene Name
OTUB1
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Product Notes
The OTUB1 otub1 (Catalog #AAA146638) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Ubiquitin Aldehyde Binding 1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ubiquitin Aldehyde Binding 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the OTUB1 otub1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ubiquitin Aldehyde Binding 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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