Fc-Epsilon RI-Alpha Recombinant Protein | FCER1A recombinant protein
Recombinant Human Fc-Epsilon RI-Alpha
Gene Names
FCER1A; FCE1A; FcERI
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Fc-Epsilon RI-Alpha; Recombinant Human Fc-Epsilon RI-Alpha; Fc Fragment Of IgE; High Affinity I; Receptor For; Alpha Polypeptide; FCE1A; IgE Fc Receptor Subunit Alpha; FcERI; Fc Epsilon RI Alpha-Chain; Fc IgE Receptor; High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit; High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha; Immunoglobulin E Receptor; High-Affinity; Of Mast Cells; FCER1A recombinant protein
Host
Escherichia Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
FCER1A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSVPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ
Physical Appearance
Sterile Filtered colorless solution.
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze thaw cycles.
Related Product Information for FCER1A recombinant protein
FCER1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (26-205aa) and having a molecular mass of 23.4kDa. FCER1A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for FCER1A recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
high affinity immunoglobulin epsilon receptor subunit alpha
NCBI Official Synonym Full Names
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
NCBI Official Symbol
FCER1A
NCBI Official Synonym Symbols
FCE1A; FcERI
NCBI Protein Information
high affinity immunoglobulin epsilon receptor subunit alpha; Fc IgE receptor, alpha polypeptide; Fc epsilon RI alpha-chain; Fc-epsilon RI-alpha; high affinity immunoglobulin epsilon receptor alpha-subunit; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
UniProt Protein Name
High affinity immunoglobulin epsilon receptor subunit alpha
Protein Family
UniProt Gene Name
FCER1A
UniProt Synonym Gene Names
FCE1A; FcERI
UniProt Entry Name
FCERA_HUMAN
NCBI Description
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
Uniprot Description
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Research Articles on FCER1A
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Product Notes
The FCER1A fcer1a (Catalog #AAA146370) is a Recombinant Protein produced from Escherichia Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSVPQ KPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ. It is sometimes possible for the material contained within the vial of "Fc-Epsilon RI-Alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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